Acute Myeloid Leukemia Clinical Trial

Clinical Trial Finder Acute Myeloid Leukemia Trials

A Trial In Patients With Advanced Cancer And Leukemia

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Summary

This is a phase 1, dose escalating study to determine the safety of PF-03084014 in patients with advanced cancer and leukemia

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Eligibility Criteria

Inclusion Criteria:

Patients with advanced cancer that is resistant to standard therapy or for which no standard therapy is available
Patients with acute T cell leukemia/lymphoblastic lymphoma that is resistant to standard therapy or for which no standard therapy is available
Men and women >16 years old

Exclusion Criteria:

Prior treatment with a gamma secretase inhibitor for treatment of cancer
Patients taking Tamoxifen
Patients with active graft versus host disease
Known human immunodeficiency virus (HIV) or acquired immunodeficiency syndrome (AIDS) related illness
Patients who are pregnant or breast feeding
Patients with clinical evidence of central nervous system disease

Study is for people with:

Acute Myeloid Leukemia

Phase:

Phase 1

Estimated Enrollment:

72

Study ID:

NCT00878189

Recruitment Status:

Completed

Sponsor:

Pfizer

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There are 7 Locations for this study

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Anschutz Cancer Pavilion
Aurora Colorado, 80045, United States
University of Colorado Denver CTRC
Aurora Colorado, 80045, United States
University of Colorado Hospital
Aurora Colorado, 80045, United States
Massachusetts General Hospital Clinical Laboratory
Boston Massachusetts, 02114, United States
Beth Israel Deaconess Medical Center
Boston Massachusetts, 02115, United States
Dana Ferber Cancer institute
Boston Massachusetts, 02215, United States
Karmanos Cancer Center / Wayne State University
Detroit Michigan, 48201, United States
The University of Texas MD Anderson Cancer Center
Houston Texas, 77030, United States
DIPRTMNT CLIN Scienze RADIOL e Istocitopatologiche
Bologna , 40138, Italy
Istituto di Ematologia Seragnoli
Bologna , 40138, Italy
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How clear is this clinincal trial information?

Study is for people with:

Acute Myeloid Leukemia

Phase:

Phase 1

Estimated Enrollment:

72

Study ID:

NCT00878189

Recruitment Status:

Completed

Sponsor:


Pfizer

How clear is this clinincal trial information?

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