Acute Myeloid Leukemia Clinical Trial

Clinical Trial Finder Acute Myeloid Leukemia Trials

Consolidation Therapy for Acute Myeloid Leukemia Guided by Leukemia Stem Cell Behavior

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Summary

The primary objective of the trial is to compare the two-year relapse-free survival (RFS) of patients with acute myeloid leukemia (AML), presumed to be at high risk for relapse due to the presence of leukemia stem cells (LSCs) in their bone marrow at first complete remission (CR1), who receive either standard cytarabine-based chemotherapy or allogeneic stem cell transplantation (SCT).

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Eligibility Criteria

Inclusion Criteria:

Age greater than or equal to 18 years
Able to give informed consent
New diagnosis of AML, other than APL or poor-risk AML, as defined in section 3.2

Exclusion criteria:

Has already had a bone marrow biopsy and aspirate to assess remission status after induction therapy
Any debilitating medical or psychiatric illness that would preclude ability to give informed consent or receive optimal treatment and follow-up
Pregnancy: Women of childbearing potential who are β- HCG+

Study is for people with:

Acute Myeloid Leukemia

Phase:

Phase 2

Estimated Enrollment:

10

Study ID:

NCT01588951

Recruitment Status:

Terminated

Sponsor:

Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins

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There is 1 Location for this study

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Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins
Baltimore Maryland, 21287, United States

How clear is this clinincal trial information?

Study is for people with:

Acute Myeloid Leukemia

Phase:

Phase 2

Estimated Enrollment:

10

Study ID:

NCT01588951

Recruitment Status:

Terminated

Sponsor:


Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins

How clear is this clinincal trial information?

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