Observational Study of Iron Overload in Stem Cell Transplantation

Inclusion Criteria:

Age ≥ 18 years.
Histologically confirmed acute myeloid leukemia (AML), acute lymphoblastic leukemia (ALL), or myelodysplastic syndrome (MDS)
Planned allogeneic stem cell transplantation with myeloablative conditioning regimen (regardless of stem cell source or donor HLA match)
Patients will be eligible even if they have had prior stem cell transplantation (autologous or allogeneic)

Exclusion Criteria:

Contraindication to magnetic resonance imaging (MRI):

Patients with cardiac pacemakers, implanted cardiac defibrillator (ICD), cardiac electrodes, pacing wires, internal electrodes, cochlear, otologic or other ear implants, metallic fragments or foreign body, metallic prosthesis. Patients with surgical staples should not be imaged until 7 days post-op unless approved by a radiologist;
Severe claustrophobia
Note: a history of allergic reaction to gadolinium is not a contraindication to enrollment, as contrast will not be used.
Inability to provide informed consent