Acute Myeloid Leukemia Clinical Trial

Trial of Daily Pulse Interleukin-2 With Famotidine in Acute Myelogenous Leukemia

Summary

Assess the immunotherapy benefit of interleukin-2 in acute myelogenous leukemia treatment during lymphocyte recovery.

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Full Description

Upon lymphocyte recovery after myeloablative induction standard chemotherapy pulse Interleukin-2 administered

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Eligibility Criteria

Inclusion Criteria:

Confirmed hematopathology diagnosis of AML receiving marrow suppressive treatment
Total WBC recovery of 500 mm3 prior to IL-2 treatment
Platelet count of at least 20,000 mm3 prior to starting IL-2 treatment
Active infection controlled prior to starting IL-2 treatment
Stable systolic blood pressure > 90mm Hg prior to starting IL-2 treatment
O2 saturation >90% prior to starting treatment
Stable cardiopulmonary status prior to starting IL-2 treatment
Serum creatinine < or equal to 2.0 mg/dl
Total bilirubin and AST <3x upper limits normal

Exclusion Criteria:

Acute Promyelocytic Leukemia
Active thrombocytopenic bleeding
Cardiac ejection fraction below 45%
Pregnancy and/or lactation

Study is for people with:

Acute Myeloid Leukemia

Phase:

Phase 2

Estimated Enrollment:

18

Study ID:

NCT01289678

Recruitment Status:

Terminated

Sponsor:

Leo W. Jenkins Cancer Center

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There is 1 Location for this study

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Leo W. Jenkins Cancer Center
Greenville North Carolina, 27834, United States

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Study is for people with:

Acute Myeloid Leukemia

Phase:

Phase 2

Estimated Enrollment:

18

Study ID:

NCT01289678

Recruitment Status:

Terminated

Sponsor:


Leo W. Jenkins Cancer Center

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