Acute Myeloid Leukemia Clinical Trial
Trial of Daily Pulse Interleukin-2 With Famotidine in Acute Myelogenous Leukemia
Summary
Assess the immunotherapy benefit of interleukin-2 in acute myelogenous leukemia treatment during lymphocyte recovery.
Full Description
Upon lymphocyte recovery after myeloablative induction standard chemotherapy pulse Interleukin-2 administered
Eligibility Criteria
Inclusion Criteria:
Confirmed hematopathology diagnosis of AML receiving marrow suppressive treatment
Total WBC recovery of 500 mm3 prior to IL-2 treatment
Platelet count of at least 20,000 mm3 prior to starting IL-2 treatment
Active infection controlled prior to starting IL-2 treatment
Stable systolic blood pressure > 90mm Hg prior to starting IL-2 treatment
O2 saturation >90% prior to starting treatment
Stable cardiopulmonary status prior to starting IL-2 treatment
Serum creatinine < or equal to 2.0 mg/dl
Total bilirubin and AST <3x upper limits normal
Exclusion Criteria:
Acute Promyelocytic Leukemia
Active thrombocytopenic bleeding
Cardiac ejection fraction below 45%
Pregnancy and/or lactation
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There is 1 Location for this study
Greenville North Carolina, 27834, United States
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