Bladder Cancer Clinical Trial

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18F-Clofarabine PET/CT in Imaging Cancer Patients Before and After Interventions

Summary

This clinical trial studies 18F-clofarabine positron emission tomography (PET)/computed tomography (CT) in imaging patients with cancer before and after treatment with a therapy that activates the patient's immune system (immunotherapy). PET/CT scans give detailed pictures of areas inside the body. 18F-clofarabine is a drug that contains a radioactive substance that is taken up by cells expressing deoxycytidine kinase (dCK), which is highly expressed in activated immune cells, making them light up during PET/CT scans. Doctors also want to know how 18F-clofarabine is distributed throughout the body before and after treatment with immunotherapies.

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Full Description

PRIMARY OBJECTIVES:

I. To determine whether positron emission tomography (PET) using the new imaging agent 18F-clofarabine can be used for imaging cancer, and whether interventions that activate the immune system can change the biodistribution of 18F-clofarabine.

OUTLINE:

Patients receive 18F-clofarabine intravenously (IV) and undergo PET/CT scan at baseline and 2-4 weeks after completion of immunotherapy.

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Eligibility Criteria

Inclusion Criteria:

Must be able to tolerate PET/CT (i.e. not claustrophobic and able to remain supine)
No restrictions based on gender or racial/ethnic background

Exclusion Criteria:

Women of childbearing age will have to undergo a pregnancy test that will be provided free of charge

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There is 1 Location for this study

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UCLA / Jonsson Comprehensive Cancer Center
Los Angeles California, 90095, United States

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Clinical Trial Finder Bladder Cancer Trials

18F-Clofarabine PET/CT in Imaging Cancer Patients Before and After Interventions

Summary

Full Description

Eligibility Criteria

Study is for people with:

Estimated Enrollment:

Study ID:

Recruitment Status:

Sponsor:

Check Your Eligibility

There is 1 Location for this study

Study is for people with:

Estimated Enrollment:

Study ID:

Recruitment Status:

Sponsor:

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Multiple Myeloma

Discover local Multiple Myeloma resources:

Ovarian Cancer

Discover local Ovarian Cancer resources:

Multiple Myeloma: Main Page

Discover local Multiple Myeloma resources:

Discover Local Multiple Myeloma resources:

Ovarian Cancer: Main Page

Discover local Ovarian Cancer resources:

Discover Local Ovarian Cancer resources:

Clinical Trial Finder Bladder Cancer Trials

18F-Clofarabine PET/CT in Imaging Cancer Patients Before and After Interventions

Summary

Full Description

Eligibility Criteria

Study is for people with:

Estimated Enrollment:

Study ID:

Recruitment Status:

Sponsor:

Check Your Eligibility

There is 1 Location for this study

Study is for people with:

Estimated Enrollment:

Study ID:

Recruitment Status:

Sponsor:

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