Bladder Cancer Clinical Trial

Perioperative Enfortumab Vedotin (EV) Plus Pembrolizumab (MK-3475) Versus Neoadjuvant Chemotherapy for Cisplatin-eligible Muscle Invasive Bladder Cancer (MIBC) (MK-3475-B15/ KEYNOTE-B15 / EV-304)

Summary

The purpose of this study is to assess the antitumor efficacy and safety of perioperative enfortumab vedotin (EV) plus pembrolizumab and radical cystectomy (RC) + pelvic lymph node dissection (PLND) compared with the current standard of care (neoadjuvant chemotherapy [gemcitabine plus cisplatin] and RC + PLND) for participants with MIBC who are cisplatin-eligible. The dual primary hypotheses are preoperative EV + pembrolizumab and RC + PLND (Arm A) will achieve superior pathologic complete response (pCR) rate and perioperative EV and pembrolizumab and RC + PLND (Arm A) will achieve superior event free survival (EFS) compared with neoadjuvant gemcitabine + cisplatin and RC + PLND (Arm B).

View Eligibility Criteria

Eligibility Criteria

Inclusion Criteria:

Have a histologically confirmed diagnosis of urothelial carcinoma (UC) / muscle invasive bladder cancer (MIBC) (T2-T4aN0M0 or T1-T4aN1M0) with predominant (≥50%) urothelial histology
Have clinically non-metastatic bladder cancer (N≤1 M0) determined by imaging (computed tomography (CT) or magnetic resonance imaging (MRI) of the chest/abdomen/pelvis
Be deemed eligible for Radical Cystectomy (RC) + Pelvic Lymph Node Dissection (PLND)
Have Eastern Cooperative Oncology Group (ECOG) performance status of 0 or 1
Have adequate organ function

Exclusion Criteria:

Has a known additional malignancy that is progressing or has required active anti-cancer treatment ≤3 years of study randomization with certain exceptions
Has received any prior systemic treatment for MIBC or non-invasive muscle bladder cancer (NMIBC - prior treatment for NMIBC with intravesical BCG/chemotherapy is permitted) or prior therapy with an anti- programmed cell death 1 (PD-1), anti-programmed cell death ligand 1/ ligand 2 (PD-L1/L2), or anti-cytotoxic T-lymphocyte-associated protein 4 (CTLA-4)
Has ≥N2 disease or metastatic disease (M1) as identified by imaging
Is cisplatin-ineligible, as defined by meeting any one of the cisplatin ineligibility criteria as per protocol
Has received prior systemic anticancer therapy including investigational agents within 3 years of randomization or any radiotherapy to the bladder
Has undergone partial cystectomy of the bladder to remove any NMIBC or MIBC
Has received a live or live attenuated vaccine within 30 days before the first dose of study intervention
Has a diagnosis of immunodeficiency or has a known history of human immunodeficiency virus (HIV) infection. Hepatitis B infection or known active Hepatitis C infection
Has a known psychiatric or substance abuse disorder
Has had an allogenic tissue/solid organ transplant
Has ongoing sensory or motor neuropathy Grade 2 or higher
Has active keratitis (superficial punctate keratitis) or corneal ulcerations
Has a history of uncontrolled diabetes defined as hemoglobin A1c (HbA1c) ≥8% or HbA1c 7% to <8% with associated diabetes symptoms

Study is for people with:

Bladder Cancer

Phase:

Phase 3

Estimated Enrollment:

784

Study ID:

NCT04700124

Recruitment Status:

Recruiting

Sponsor:

Merck Sharp & Dohme LLC

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There are 149 Locations for this study

See Locations Near You

Mayo Clinic in Arizona - Phoenix ( Site 0043)
Phoenix Arizona, 85054, United States More Info
Study Coordinator
Contact
480-342-2000
St Joseph Heritage Healthcare-Oncology ( Site 0035)
Fullerton California, 92835, United States
UCLA Hematology/Oncology - Westwood (Building 200 Suite 140)-Department of Urology/Institute of Uro
Los Angeles California, 90095, United States More Info
Study Coordinator
Contact
310-451-8751
University of California San Francisco ( Site 0010)
San Francisco California, 94158, United States More Info
Study Coordinator
Contact
773-837-0783
Stanford University ( Site 0023)
Stanford California, 94305, United States More Info
Study Coordinator
Contact
650-725-2078
University of Colorado, Anschutz Cancer Pavilion ( Site 0009)
Aurora Colorado, 80045, United States More Info
Study Coordinator
Contact
303-724-0499
UF Health ( Site 0031)
Gainesville Florida, 32608, United States More Info
Study Coordinator
Contact
352-265-0725
Indiana University Melvin and Bren Simon Cancer Center ( Site 0050)
Indianapolis Indiana, 46202, United States More Info
Study Coordinator
Contact
317-944-5349
University of Iowa Hospital and Clinics ( Site 0029)
Iowa City Iowa, 52242, United States More Info
Study Coordinator
Contact
319-384-8076
University of Louisville, James Graham Brown Cancer Center ( Site 0022)
Louisville Kentucky, 40202, United States More Info
Study Coordinator
Contact
502-562-3429
Icahn School of Medicine at Mount Sinai ( Site 0011)
New York New York, 10029, United States More Info
Study Coordinator
Contact
212-659-5452
White Plains Hospital ( Site 0039)
White Plains New York, 10601, United States More Info
Study Coordinator
Contact
914-849-7630
Duke University Medical Center ( Site 0017)
Durham North Carolina, 27710, United States More Info
Study Coordinator
Contact
919-613-4494
Wake Forest Baptist Health ( Site 0014)
Winston-Salem North Carolina, 27157, United States More Info
Study Coordinator
Contact
336-713-5440
Oregon Health and Science University ( Site 0028)
Portland Oregon, 97239, United States More Info
Study Coordinator
Contact
503-346-8089
MidLantic Urology ( Site 0002)
Bala-Cynwyd Pennsylvania, 19004, United States More Info
Study Coordinator
Contact
610-667-0458
Saint Francis Cancer Center ( Site 0008)
Greenville South Carolina, 29607, United States More Info
Study Coordinator
Contact
863-603-6300
The University of Tennessee Medical Center ( Site 0034)
Knoxville Tennessee, 37920, United States
UT Southwestern Medical Center ( Site 0003)
Dallas Texas, 75390, United States More Info
Study Coordinator
Contact
214-648-6585
Houston Methodist Urology Associates ( Site 0033)
Houston Texas, 77030, United States More Info
Study Coordinator
Contact
346-238-6123
Urology of San Antonio ( Site 0020)
San Antonio Texas, 78229, United States More Info
Study Coordinator
Contact
210-614-4116
University of Wisconsin Hospital and Clinics ( Site 0037)
Madison Wisconsin, 53792, United States More Info
Study Coordinator
Contact
800-622-8922
Mater Hospital Brisbane ( Site 1257)
South Brisbane Queensland, 4101, Australia
Lyell McEwin Hospital ( Site 1252)
Elizabeth Vale South Australia, 5112, Australia More Info
Study Coordinator
Contact
+61882820833
Frankston Hospital-Oncology and Haematology ( Site 1258)
Frankston Victoria, 3199, Australia More Info
Study Coordinator
Contact
+61425733507
Complex Oncology Center Plovdiv ( Site 1151)
Plovdiv , 4000, Bulgaria More Info
Study Coordinator
Contact
+359899822788
MHAT Central Onco Hospital OOD ( Site 1158)
Plovdiv , 4000, Bulgaria More Info
Study Coordinator
Contact
+359888431354
MHAT Serdika ( Site 1152)
Sofia , 1632, Bulgaria More Info
Study Coordinator
Contact
+359888223107
BC Cancer - Vancouver Center ( Site 0110)
Vancouver British Columbia, V5Z 4, Canada More Info
Study Coordinator
Contact
6048776000
Moncton Hospital ( Site 0107)
Moncton New Brunswick, E1C 6, Canada More Info
Study Coordinator
Contact
506-857-5669
Ottawa Hospital Research Institute ( Site 0109)
Ottawa Ontario, K1H 8, Canada More Info
Study Coordinator
Contact
613-737-7700
Jewish General Hospital ( Site 0106)
Montreal Quebec, H3T 1, Canada More Info
Study Coordinator
Contact
514-340-8222
SUN YAT-SEN UNIVERSITY CANCER CENTRE ( Site 1406)
Guangzhou Guangdong, 51006, China More Info
Study Coordinator
Contact
020-87343585
Sun Yat-sen Memorial Hospital, Sun Yat-sen University ( Site 1413)
Guangzhou Guangdong, 51012, China More Info
Study Coordinator
Contact
020-34071255
Hunan Cancer Hospital ( Site 1403)
Changsha Hunan, 41001, China More Info
Study Coordinator
Contact
+86073188651900
Nanjing Drum Tower Hospital The Affiliated Hospital of Nanjing University Medical School-Urology ( S
Nanjing Jiangsu, 21000, China More Info
Study Coordinator
Contact
02568182222
Nantong Tumor Hospital-Urology ( Site 1405)
Nantong Jiangsu, 22636, China More Info
Study Coordinator
Contact
15950868500
Fudan University Shanghai Cancer Center-Urology department ( Site 1401)
Shanghai Shanghai, 20003, China More Info
Study Coordinator
Contact
13701663571
Fakultni nemocnice u sv. Anny v Brne ( Site 0253)
Brno Jihomoravsky Kraj, 656 9, Czechia More Info
Study Coordinator
Contact
+420543183073
Fakultni nemocnice Hradec Kralove-Klinika onkologie a radioterapie ( Site 0254)
Hradec Kralove , 500 0, Czechia More Info
Study Coordinator
Contact
+420495834980
Fakultni Nemocnice Olomouc ( Site 0251)
Olomouc , 779 0, Czechia More Info
Study Coordinator
Contact
+420588444288
Fakultni Thomayerova nemocnice ( Site 0252)
Praha 4 , 140 5, Czechia More Info
Study Coordinator
Contact
00420261083530
CHU La Timone ( Site 0456)
Marseille Bouches-du-Rhone, 13005, France More Info
Study Coordinator
Contact
+33491385708
CHU Jean Minjoz ( Site 0453)
Besancon Doubs, 25000, France More Info
Study Coordinator
Contact
+33370632403
CHU de Brest -Site Hopital Morvan ( Site 0461)
Brest Finistere, 29200, France More Info
Study Coordinator
Contact
+33298223395
Institut Universitaire du Cancer Toulouse - Oncopole ( Site 0455)
Toulouse Haute-Garonne, 31059, France More Info
Study Coordinator
Contact
+33531155993
CHU Limoges Hopital Dupuytren ( Site 0459)
Limoges Haute-Vienne, 87042, France More Info
Study Coordinator
Contact
+33555056396
Gustave Roussy ( Site 0467)
Villejuif Ile-de-France, 94800, France More Info
Study Coordinator
Contact
+33142115348
Centre Hospitalier Regional du Orleans ( Site 0463)
Orleans Loiret, 45067, France More Info
Study Coordinator
Contact
+33238514444
Polyclinique du Bois ( Site 0458)
Lille Nord, 59000, France More Info
Study Coordinator
Contact
+33 320009757
Hopital Diaconesses Croix Saint Simon ( Site 0465)
Paris , 75020, France More Info
Study Coordinator
Contact
+33144742839
Universitaetsklinikum Freiburg ( Site 0512)
Freiburg Baden-Wurttemberg, 79106, Germany More Info
Study Coordinator
Contact
4976127028930
Universitaetsklinik fuer Urologie ( Site 0501)
Tuebingen Baden-Wurttemberg, 72076, Germany More Info
Study Coordinator
Contact
+4970712985268
Caritas Krankenhaus St. Josef ( Site 0502)
Regensburg Bayern, 93053, Germany More Info
Study Coordinator
Contact
+499417820
Kath. Krankenhaus Marienhospital. Universitaetsklinik ( Site 0511)
Herne Nordrhein-Westfalen, 44625, Germany More Info
Study Coordinator
Contact
+4923234991660
Universitaetsklinikum Muenster ( Site 0516)
Muenster Nordrhein-Westfalen, 48149, Germany More Info
Study Coordinator
Contact
492518348001
Krankenhaus Martha Maria Halle-Doelau ( Site 0507)
Halle Sachsen-Anhalt, 06120, Germany More Info
Study Coordinator
Contact
+493455591449
Universitaetsklinikum Carl Gustav Carus ( Site 0509)
Dresden Sachsen, 01307, Germany More Info
Study Coordinator
Contact
00493514582157
UNIVERSITY HOSPITAL OF PATRAS-DIVISION OF ONCOLOGY ( Site 0305)
Patras Achaia, 26504, Greece More Info
Study Coordinator
Contact
+302610999791
General Hospital of Athens "Alexandra" ( Site 0303)
Athens Attiki, 115 2, Greece More Info
Study Coordinator
Contact
0302132162513
Athens Medical Center ( Site 0304)
Athens Attiki, 151 2, Greece More Info
Study Coordinator
Contact
+302106157392
ATTIKON GENERAL UNIVERSITY HOSPITAL ( Site 0301)
Chaidari Attiki, 124 6, Greece More Info
Study Coordinator
Contact
+302105831255
University General Hospital of Larissa ( Site 0302)
Larissa Thessalia, 411 1, Greece More Info
Study Coordinator
Contact
+302413502027
Rambam Health Care Campus-Oncology ( Site 0751)
Haifa , 31096, Israel More Info
Study Coordinator
Contact
+972-4-7776400
Hadassah Medical Center-Oncology ( Site 0757)
Jerusalem , 91120, Israel More Info
Study Coordinator
Contact
972505172315
Meir Medical Center-oncology ( Site 0754)
Kfar Saba , 44281, Israel More Info
Study Coordinator
Contact
97297472337
Rabin Medical Center-Oncology ( Site 0752)
Petah-Tikva , 49414, Israel More Info
Study Coordinator
Contact
97239378074
Sheba Medical Center-ONCOLOGY ( Site 0753)
Ramat Gan , 52621, Israel More Info
Study Coordinator
Contact
+972-3-5302191
Sourasky Medical Center-Oncology ( Site 0755)
Tel Aviv , 64239, Israel More Info
Study Coordinator
Contact
+97236947616
Yitzhak Shamir Medical Center-Oncology ( Site 0756)
Zerifin , 70300, Israel More Info
Study Coordinator
Contact
972 8 9779715
Presidio Ospedaliero Santa Maria delle Grazie ( Site 0599)
Pozzuoli Napoli, 80078, Italy More Info
Study Coordinator
Contact
08118844048
AOU San Luigi Gonzaga di Orbassano ( Site 0595)
Orbassano Torino, 10043, Italy More Info
Study Coordinator
Contact
+390119026993
Istituto Oncologico Veneto IRCCS-Oncologia Medica 1 ( Site 0600)
Padova Veneto, 35128, Italy More Info
Study Coordinator
Contact
+390498215908
Azienda Ospedaliera Universitaria Integrata Verona - Ospedale Borgo Trento ( Site 0598)
Verona Veneto, 1932, Italy More Info
Study Coordinator
Contact
390458122768
Ospedali Riuniti Umberto I GM Lancis G Salesi ( Site 0593)
Ancona , 60126, Italy More Info
Study Coordinator
Contact
+390715964169
Ospedale Cannizzaro ( Site 0590)
Catania , 95126, Italy More Info
Study Coordinator
Contact
+39 3487142015
IRCCS Ospedale San Raffaele ( Site 0596)
Milano , 20132, Italy More Info
Study Coordinator
Contact
+390226435789
Nagoya University Hospital ( Site 1512)
Nagoya Aichi, 466-8, Japan More Info
Study Coordinator
Contact
+81-52-741-2111
Hirosaki University Hospital ( Site 1501)
Hirosaki Aomori, 036-8, Japan More Info
Study Coordinator
Contact
+81-172-33-5111
University of Tsukuba Hospital ( Site 1502)
Tsukuba Ibaraki, 305-8, Japan More Info
Study Coordinator
Contact
+81-29-853-3900
Kanazawa University Hospital ( Site 1509)
Kanazawa Ishikawa, 920-8, Japan More Info
Study Coordinator
Contact
+81-76-265-2000
Yokohama City University Medical Center ( Site 1508)
Yokohama Kanagawa, 232-0, Japan More Info
Study Coordinator
Contact
+81-45-261-5656
Kanagawa Cancer Center ( Site 1507)
Yokohama Kanagawa, 241-8, Japan More Info
Study Coordinator
Contact
+81-45-520-2222
Tohoku University Hospital ( Site 1503)
Sendai Miyagi, 980-8, Japan More Info
Study Coordinator
Contact
+81-22-717-7000
Hamamatsu University Hospital ( Site 1511)
Hamamatsu Shizuoka, 431-3, Japan More Info
Study Coordinator
Contact
+81-53-435-2111
Gifu University Hospital ( Site 1513)
Gifu , 501-1, Japan More Info
Study Coordinator
Contact
+81-58-230-6000
Nagasaki University Hospital ( Site 1517)
Nagasaki , 852-8, Japan More Info
Study Coordinator
Contact
+81-95-819-7200
Okayama University Hospital ( Site 1516)
Okayama , 70085, Japan More Info
Study Coordinator
Contact
+81-86-223-7151
Osaka International Cancer Institute ( Site 1514)
Osaka , 541-8, Japan More Info
Study Coordinator
Contact
+81-6-6945-1181
Osaka Metropolitan University Hospital ( Site 1515)
Osaka , 545-8, Japan More Info
Study Coordinator
Contact
+81-6-6645-2121
Keio University Hospital ( Site 1504)
Tokyo , 160-8, Japan More Info
Study Coordinator
Contact
+81-3-3353-1211
Tokyo Medical and Dental University Hospital ( Site 1505)
Tokyo , , Japan More Info
Study Coordinator
Contact
+81-3-3813-6111
Toyama University Hospital ( Site 1510)
Toyama , 930-0, Japan More Info
Study Coordinator
Contact
+81-76-434-2281
Chonnam National University Hwasun Hospital ( Site 1353)
Jeollanam-do Jeonranamdo, 58128, Korea, Republic of More Info
Study Coordinator
Contact
+82613797745
Seoul National University Bundang Hospital ( Site 1355)
Gyeonggi-do Kyonggi-do, 13620, Korea, Republic of More Info
Study Coordinator
Contact
+82317877351
Asan Medical Center ( Site 1352)
Songpagu Seoul, 05505, Korea, Republic of More Info
Study Coordinator
Contact
82230103980
Kyungpook National University Chilgok Hospital ( Site 1354)
Daegu Taegu-Kwangyokshi, 41404, Korea, Republic of More Info
Study Coordinator
Contact
+82532002672
Gachon University Gil Medical Center ( Site 1356)
Incheon , 21565, Korea, Republic of More Info
Study Coordinator
Contact
+82324603231
Seoul National University Hospital ( Site 1351)
Seoul , 03080, Korea, Republic of More Info
Study Coordinator
Contact
+82220720361
University Malaya Medical Centre ( Site 0352)
Lembah Pantai Kuala Lumpur, 59100, Malaysia More Info
Study Coordinator
Contact
+60379492120
Hospital Pulau Pinang ( Site 0355)
George Town Pulau Pinang, 10990, Malaysia More Info
Study Coordinator
Contact
+604 222 5711
Sarawak General Hospital ( Site 0351)
Kuching Sarawak, 93586, Malaysia More Info
Study Coordinator
Contact
+6082-276666 ext. 6030
Sunway Medical Centre ( Site 0353)
Petaling Jaya Selangor, 47500, Malaysia More Info
Study Coordinator
Contact
+603 7491 9191
Mazowiecki Szpital Wojewódzki w Siedlcach-Siedleckie Centrum Onkologii ( Site 1057)
Siedlce Mazowieckie, 08-11, Poland More Info
Study Coordinator
Contact
+48 25 64 03 485
Narodowy Instytut Onkologii ( Site 1051)
Warszawa Mazowieckie, 02-78, Poland More Info
Study Coordinator
Contact
+48225462331
Wojewodzki Szpital im. Sw. Ojca Pio w Przemyslu ( Site 1053)
Przemysl Podkarpackie, 37-70, Poland More Info
Study Coordinator
Contact
+48 16 677 55 11
Clinical Research Center Medic-R ( Site 1061)
Poznan Wielkopolskie, 61-73, Poland More Info
Study Coordinator
Contact
+48500799053
Szpital Wojewodzki im. Mikolaja Kopernika ( Site 1055)
Koszalin Zachodniopomorskie, 75-58, Poland More Info
Study Coordinator
Contact
+48502204953
Centro Hospitalar e Universitario de Coimbra ( Site 0406)
Coimbra , 3000-, Portugal More Info
Study Coordinator
Contact
+351239400457
Inst. Portugues de Oncologia de Lisboa Francisco Gentil EPE ( Site 0409)
Lisboa , 1099-, Portugal More Info
Study Coordinator
Contact
+351217229800
CHLO, EPE - Hospital de Sao Francisco Xavier ( Site 0401)
Lisboa , 1449-, Portugal More Info
Study Coordinator
Contact
+351210431704
Hospital Geral de Santo Antonio ( Site 0408)
Porto , 4099-, Portugal More Info
Study Coordinator
Contact
+351222077500
Institutul Oncologic Prof.Dr. Ion Chiricuta Cluj-Napoca ( Site 1102)
Cluj Napoca Cluj, 40001, Romania More Info
Study Coordinator
Contact
+40745976913
Cardiomed SRL Cluj-Napoca ( Site 1101)
Cluj-Napoca Cluj, 40001, Romania More Info
Study Coordinator
Contact
+40721254415
Institutul Oncologic Prof.Dr. Ion Chiricuta Cluj-Napoca ( Site 1103)
Cluj-Napoca Cluj, 40001, Romania More Info
Study Coordinator
Contact
+4026459831
SC Radiotherapy Center Cluj SRL ( Site 1108)
Comuna Floresti Cluj, 40728, Romania More Info
Study Coordinator
Contact
+40742206212
S.C. Centrul de Oncologie Sf. Nectarie SRL ( Site 1107)
Craiova Dolj, 20034, Romania More Info
Study Coordinator
Contact
40727774974
Policlinica Oncomed SRL ( Site 1106)
Timisoara Timis, 30023, Romania More Info
Study Coordinator
Contact
+40256495403
SC Focus Lab Plus SRL ( Site 1104)
Bucuresti , 02254, Romania More Info
Study Coordinator
Contact
+40721298677
Altay Regional Oncology Dispensary ( Site 0851)
Barnaul Altayskiy Kray, 65604, Russian Federation
National Medical Research Radiology Centre ( Site 0869)
Obninsk Kaluzskaja Oblast, 24903, Russian Federation
National Medical Research Centre of Oncology named after N.N. Blokhin ( Site 0865)
Moscow Moskva, 11523, Russian Federation
First Moscow State Medical University n.a. I.M.Sechenov ( Site 0871)
Moscow Moskva, 11999, Russian Federation
Volga District Medical Center ( Site 0876)
Nizhny Novgorod Nizhegorodskaya Oblast, 60307, Russian Federation
St.Petersburg Clinical Hospital RAS ( Site 0864)
Saint Petersburg Sankt-Peterburg, 19401, Russian Federation
St.Petersburg State Medical Univ. n.a. acad. I.P.Pavlov ( Site 0856)
Saint Petersburg Sankt-Peterburg, 19710, Russian Federation
Scientific Research Oncology Institute n.a. N.N.Petrov ( Site 0852)
Saint Petersburg Sankt-Peterburg, 19775, Russian Federation
Sverdlovsk Regional Oncology Hospital ( Site 0867)
Ekaterinburg Sverdlovskaya Oblast, 62003, Russian Federation
Sverdlovsky Regional Clinical hospital #1 ( Site 0868)
Ekaterinburg Sverdlovskaya Oblast, 62010, Russian Federation
Volgograd Regional Uronephrological Center ( Site 0870)
Volzhsky Volgogradskaya Oblast, 40412, Russian Federation
Tan Tock Seng Hospital ( Site 0704)
Singapore Central Singapore, 39844, Singapore More Info
Study Coordinator
Contact
+6562566011
Wits Clinical Research ( Site 0603)
Johannesburg Gauteng, 2193, South Africa More Info
Study Coordinator
Contact
27113390600
Steve Biko Academic Hospital ( Site 0601)
Pretoria Gauteng, 0002, South Africa More Info
Study Coordinator
Contact
+27123466701
Groote Schuur Hospital ( Site 0602)
Cape Town Western Cape, 7925, South Africa More Info
Study Coordinator
Contact
+27(0)214044265
Hospital Universitario Central de Asturias ( Site 0654)
Oviedo Asturias, 33011, Spain More Info
Study Coordinator
Contact
+34985106121
Hospital Germans Trias i Pujol. ICO de Badalona ( Site 0658)
Badalona Barcelona, 08916, Spain More Info
Study Coordinator
Contact
+34934651200
Xarxa Assistencial Universitaria Manresa ( Site 0655)
Manresa Barcelona, 08243, Spain More Info
Study Coordinator
Contact
+34938759300
Hospital Universitari de Girona Doctor Josep Trueta ( Site 0653)
Girona Gerona, 17007, Spain More Info
Study Coordinator
Contact
+34972225832
CHUS - Hospital Clinico Universitario-Servicio de Oncologia ( Site 0660)
Santiago de Compostela La Coruna, 15706, Spain More Info
Study Coordinator
Contact
+34981950511
Hospital Universitario Insular de Gran Canaria ( Site 0657)
Las Palmas de Gran Canaria Las Palmas, 35001, Spain More Info
Study Coordinator
Contact
+34961452191
Fundación Instituto Valenciano de Oncología-Oncologico ( Site 0662)
Valencia Valenciana, Comunitat, 46009, Spain More Info
Study Coordinator
Contact
+34961114229
Hospital Universitari Vall d'Hebron-Departamento de Oncologia- VHIO ( Site 0661)
Barcelona , 08035, Spain More Info
Study Coordinator
Contact
+34934894350
Hospital Clinico Universitario San Carlos de Madrid ( Site 0651)
Madrid , 28040, Spain More Info
Study Coordinator
Contact
+34913303000 x7554
Hospital Virgen del Rocio ( Site 0659)
Sevilla , 41013, Spain More Info
Study Coordinator
Contact
+34955012000
China Medical University Hospital ( Site 1202)
Taichung , 40433, Taiwan More Info
Study Coordinator
Contact
04-22052121 #2955
Taipei Veterans General Hospital ( Site 1201)
Taipei , 11217, Taiwan More Info
Study Coordinator
Contact
886-2-28757519 ext. 306
I.I. Mechnykov Dnipropetrovsk Regional Clinical Hospital ( Site 0959)
Dnipro Dnipropetrovska Oblast, 49005, Ukraine
MI Clinical oncology dispensary of Dnipropetrovsk regional council ( Site 0954)
Dnipro Dnipropetrovska Oblast, 49055, Ukraine
Regional Clinical Center of Urology and Nephrology n.a. V.I. Shapoval ( Site 0952)
Kharkiv Kharkivska Oblast, 61037, Ukraine
MNPE Regional Center of Oncology ( Site 0955)
Kharkiv Kharkivska Oblast, 61070, Ukraine More Info
Study Coordinator
Contact
+380573151591
Municipal Non-profit Enterprise of Kharkiv Regional Council RCSDRPP ( Site 0965)
Kharkiv Kharkivska Oblast, 61166, Ukraine
Lviv Oncology Regional Treatment and Diagnostic Center ( Site 0960)
Lviv Lvivska Oblast, 79031, Ukraine
Zhytomyr Regional Oncology Center ( Site 0961)
Zhytomyr Zhytomyrska Oblast, 10002, Ukraine

How clear is this clinincal trial information?

Study is for people with:

Bladder Cancer

Phase:

Phase 3

Estimated Enrollment:

784

Study ID:

NCT04700124

Recruitment Status:

Recruiting

Sponsor:


Merck Sharp & Dohme LLC

How clear is this clinincal trial information?

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