Breast Cancer Clinical Trial

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A Study of LY3295668 Erbumine in Participants With Breast Cancer That Has Spread to Other Parts of the Body

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Summary

The reason for this study is to determine the recommended phase 2 dose of the study drug LY3295668 erbumine in participants with breast cancer that has spread to other parts of the body.

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Eligibility Criteria

Inclusion Criteria:

Participant must have hormone receptor positive and HER2 negative metastatic breast cancer
Participant must have progressed on at least 1 line of endocrine therapy and 1 cyclin dependent kinase (CDK)4/6 inhibitor
Participant must be able and willing to undergo mandatory tumor biopsy
Participant must have normal organ function
Participant must be able to swallow capsules

Exclusion Criteria:

Participant must not have had prior chemotherapy for mBC. Chemotherapy in the adjuvant/neoadjuvant setting is permitted
Participant must not be currently enrolled in a clinical study
Participant must not have another serious medical condition
Participant must not have previously received an aurora kinase inhibitor

Study is for people with:

Breast Cancer

Phase:

Phase 1

Estimated Enrollment:

5

Study ID:

NCT03955939

Recruitment Status:

Completed

Sponsor:

Eli Lilly and Company

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There are 7 Locations for this study

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City of Hope National Medical Center
Duarte California, 91010, United States
Dana Farber Cancer Institute
Boston Massachusetts, 02115, United States
South Texas Accelerated Research Therapeutics, LLC
San Antonio Texas, 78229, United States
Cliniques Universitaires Saint-Luc
Brussels , 1200, Belgium
Universitair Ziekenhuis Antwerpen
Edegem , 2650, Belgium
Universitair Ziekenhuis Gent
Gent , 9000, Belgium
Universitaire Ziekenhuizen Leuven - Campus Gasthuisberg
Leuven , 3000, Belgium
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How clear is this clinincal trial information?

Study is for people with:

Breast Cancer

Phase:

Phase 1

Estimated Enrollment:

5

Study ID:

NCT03955939

Recruitment Status:

Completed

Sponsor:


Eli Lilly and Company

How clear is this clinincal trial information?

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