A Yoga and Wellness Program for Breast Cancer Survivors With Persistent Fatigue

Inclusion Criteria:

Diagnosed with early, resectable breast cancer (Stage I or II)
Completed treatment with surgery, radiation, and/or chemotherapy between 6 months and 5 years previously
No other cancer in last 5 years, including breast cancer recurrence
Postmenopausal women
Age 40 - 65
Reporting persistent cancer-related fatigue

Exclusion Criteria:

Evidence that fatigue is directly related to a medical or psychiatric disorder (e.g., untreated hypothyroidism, diabetes, anemia (defined as hematocrit < 24), chronic fatigue syndrome, current major depression, insomnia, sleep apnea, restless leg syndrome)
Evidence that fatigue is related to other non-cancer related factors (e.g., shift work, recent change in activity or schedule)
Physical problems or conditions that could make yoga unsafe (e.g., serious neck injuries, unstable joints; also severe cachexia, dizziness, bone pain, severe nausea, etc)
Regular use of medications and/or behavioral therapies that would confound evaluation of IY, including regular participation in yoga classes
Presence of medical conditions that involve the immune system and would confound immune evaluation (e.g., autoimmune disorder, inflammatory disease)
Use of medications that might confound immune evaluation (e.g., regular use of corticosteroids, narcotics, opiates)
Unable to commit to intervention schedule
Body mass index greater than 30 kg/m2
Regular tobacco (defined as daily or near daily) or alcohol use (defined as > 2 drinks/day)