Cancer Survival Through Weight Loss and Exercise

Inclusion Criteria:

Women between the ages of 30 and 75.
Positive history of breast cancer treatment completed at least 2 months but no longer than 36 months prior to randomization.
BMI ≥ 25 kg/m2 and ≤ 45 kg/m2
Not involved in regular physical activity or weight loss management programs.
Stage I, II or IIIa breast cancer with good prognosis.

Exclusion Criteria:

Presence of any co-morbidities including cardiovascular disease or diabetes
Fasting triglycerides > 500 mg/dl.
Consume more than 14 alcoholic beverages per week.
A history of drug abuse, or excess alcohol consumption (40g/day)6.
Currently dieting or engaging in any activity with the goal of losing weight.
Significant intentional weight loss in the past year (> 50 lbs in the past year) or current use of weight loss medications.
History of gastrointestinal bypass or other bariatric surgery in the last 3 years.
Pregnant or plan on becoming pregnant in the next 12 months.
Factors that may limit adherence to intervention or affect conduct of the trial.
Unable or unwilling to communicate with staff, to provide written informed consent, or accept the randomized assignment.
Failure to complete run-in and baseline testing.
Lack support from health care provider or family members.
Other temporary intervening event, such as sick spouse, bereavement, or recent move.
Any other medical condition or disease that is life threatening or that can interfere with or be aggravated by exercise.
Current diagnosis of schizophrenia, other psychotic disorders, or bipolar disorder.
Any other condition, which, in the opinion of the investigators would impede competence or compliance or possibly hinder completion of the study.