The purpose of this study is to determine if Contrast Enhanced Spectral Mammography (CESM) will be able to detect smaller/earlier breast cancers as well as breast MRI can.
Women considered at increased risk for developing breast carcinoma (those with a lifetime risk of >15%due to family history, genetic predisposition, prior radiation therapy to the chest, prior biopsy showing a high risk lesion, or personal history of breast cancer) that are being screened with breast MRI. Women who have a screening digital mammogram on the day of CESM or within 365 days prior
Exclusion Criteria:
Women under 21. Pregnant or possibly pregnant. Women who have a contraindication to the intravenous use of iodinated - contrast agent (i.e., allergy to iodinated contrastor severely impaired renal function with a creatinine level > or = to 1.3). Women with breast implants. Women with pacemakers. Women with aneurysm clips that don't allow for MRI. Women too claustrophobic to undergo MRI.
