Breast Cancer Clinical Trial

Comparison of MRI and CEDM to Evaluate Treatment Response Before Surgery

Summary

The purpose of this study is to compare the diagnostic accuracy of breast magnetic resonance imaging (MRI) and contrast enhanced digital mammography (CEDM) in assessing the residual disease extent in patients who have completed neoadjuvant therapy (NAT).

View Eligibility Criteria

Eligibility Criteria

Inclusion Criteria:

Any woman who has completed or is nearing completion of neoadjuvant therapy for breast cancer and is scheduled for a post-NAT breast MRI and mammogram
Surgery (mastectomy or BCT) planned within 60 days of the MRI

Exclusion Criteria:

Women who have a contraindication to the intravenous use of iodinated contrast agent (i.e., allergy to iodinated contrast or severely impaired renal function with a creatinine level > 1.3 or eGFR ≥45)
Known allergic reaction to gadolinium; patient may be eligible if the referring physician determines that the MRI is medically necessary and if the patient is willing to undergo pre-medication for contrast allergy
Pregnant women
Male patients
Presence of non MR compatible metallic objects or metallic objects that, in the opinion of the radiologist, would make MRI a contraindication
Known or suspected renal impairment. Requirements for GFR prior to MRI as determined by local site standard practice
Women who have already had their standard of care post-NAT mammogram and/or breast MRI

Study is for people with:

Breast Cancer

Estimated Enrollment:

125

Study ID:

NCT03070340

Recruitment Status:

Active, not recruiting

Sponsor:

Memorial Sloan Kettering Cancer Center

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There are 5 Locations for this study

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Memoral Sloan Kettering Basking Ridge (Consent only)
Basking Ridge New Jersey, 07920, United States
Memorial Sloan Kettering Bergen (Consent only)
Montvale New Jersey, 07645, United States
Memorial Sloan Kettering Commack (Consent only)
Commack New York, 11725, United States
Memoral Sloan Kettering Westchester (Consent only)
Harrison New York, 10604, United States
Memorial Sloan Kettering Cancer Center
New York New York, 10021, United States

How clear is this clinincal trial information?

Study is for people with:

Breast Cancer

Estimated Enrollment:

125

Study ID:

NCT03070340

Recruitment Status:

Active, not recruiting

Sponsor:


Memorial Sloan Kettering Cancer Center

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