Breast Cancer Clinical Trial
Glucose Monitoring to Predict and Treat High Glucose Levels After Steroid Treatment
Summary
The purpose of this study is to see if continuous glucose monitoring can identify how often people who have pre-diabetes or medical obesity or well-controlled diabetes experience very high glucose values while receiving chemotherapy for breast cancer or pancreatic.
Eligibility Criteria
Inclusion Criteria:
Patient aged 18 or older undergoing neoadjuvant chemotherapy regimens including taxane and/or anthracycline for breast cancer.
Patient aged 18 or older undergoing any chemotherapy regimen for pancreatic cancer
Have 'high metabolic risk(either pre-diabetes, obesity, or well-controlled diabetes) defined as either:
Pre-diabetes and/or obesity group: one or more of known HbA1c 5.7-6.5%, fasting glucose > 100 mg/dL, or BMI > 30
Well-controlled diabetes: Known HbA1c < 7.5 on lifestyle alone or up to one oral antidiabetic agent
Any patient undergoing treatment for pancreatic adenocarcinoma on either no antidiabetic agent or up to one oral antidiabetic agent
Exclusion Criteria:
Patients with type 1 diabetes, a history of hospitalization for either hyperglycemia or ketoacidosis, a history of hypoglycemia requiring hospitalization, rashes or other skin reactions that would preclude placement of the CGM
Use of anticoagulants or antiplatelet agents other than aspirin
Platelet count < 50 K/μL within 60 days prior to enrollment.
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