Heading Off Peripheral Neuropathy With Exercise

Inclusion Criteria:

age 19 or older with newly diagnosed Stage I-IIIa invasive breast cancer who are to be treated with a taxane-based chemotherapy regimen (with paclitaxel or docetaxel) and thus are at risk for the development of CIPN.

Exclusion Criteria:

any disease (e.g. diabetes, HIV) that results in peripheral neuropathy;
any disease or disorder that results in muscle weakness (such as chronic fatigue syndrome, multiple sclerosis, spinal cord tumors or injuries, stroke, preexisting cardiopulmonary disease);
any disease or disorder that would preclude strength training exercises (such as bone metastasis, osteoporosis);
individuals with diagnosed lymphedema or advanced disease (> Stage IIIa, or metastatic disease) at high risk for bone metastases and pathologic fracture will be excluded.