High-Intensity Interval Training for Stage I-III Breast Cancer Patients

Inclusion Criteria:

English or Spanish speaking
Diagnosed with early stage (I-III) breast cancer, without evidence of metastatic disease
Planned (neo)adjuvant therapy with trastuzumab (Herceptin) and/or anthracycline-based chemotherapy
Not currently pregnant or planning to become pregnant throughout the duration of cancer treatment
Physician (oncologist) clearance to participate in exercise at moderate to high intensity
Have read and signed study informed consent document (ICF)
EXERCISE INCLUSION CRITERIA:
Normal body temperature (=< 100 degrees F)
Resting blood pressure and/or heart rate within normal limits
Participants have not received intravenous or oral chemotherapy on the same day and prior to scheduled exercise session

Exclusion Criteria:

Advanced stage (stage IV) or metastatic breast cancer diagnosis (screening for metastases with scans only needed if there is clinical suspicion for metastases)
Medical history of coronary heart or artery disease, chronic or acute congestive heart failure or history of systolic or diastolic insufficiencies
Uncontrolled hypertension or other uncontrolled chronic disease (e.g. diabetes mellitus, thyroid disease, pulmonary disease, etc.)
Moderate to highly active level of physical activity (e.g. currently participating in >= 60 minutes of moderate aerobic activity weekly)
Orthopedic or other restrictions or contraindications to high-intensity (cycling) exercise
EXERCISE EXCLUSION CRITERIA:
Presence of fever (>= 100 degrees F)
Resting blood pressure and/or heart rate outside normal limits
Participants have received intravenous or oral chemotherapy on the same day and prior to scheduled exercise session