Breast Cancer Clinical Trial

HOPE-Genomics Intervention for the Improvement of Cancer Patient Knowledge of Genomics

Summary

This clinical trial studies the effectiveness of a web-based cancer education tool called Helping Oncology Patients Explore Genomics (HOPE-Genomics) in improving patient knowledge of personal genomic testing results and cancer and genomics in general. HOPE-Genomics is a web-based education tool that teaches cancer/leukemia patients, and patients who may be at high-risk for developing cancer, about genomic testing and provide patients with information about their own genomic test results. The HOPE-Genomics tool may improve patient's genomic knowledge and quality of patient-centered care. In addition, it may also improve education and care quality for future patients.

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Full Description

PRIMARY OBJECTIVES:

I. Test the efficacy of the HOPE-Genomics intervention in improving patient knowledge of genomics.

II. Test the efficacy of the HOPE-Genomics intervention in improving patient receipt of guideline-concordant care.

OUTLINE: Patients are randomized to 1 of 3 arms.

ARM I (USUAL CARE): Patients receive education pamphlet about whole-genome sequencing (WES) and have their genomics test results returned by their clinician in a typical manner.

ARM II (RETURN OF RESULTS ONLY): Patients receive their genomics test results both from their clinician and from the HOPE-Genomics tool. Patients then view HOPE-Genomics tool over 15-20 minutes after their results are available.

ARM III (RETURN OF RESULTS PLUS PRE-TEST EDUCATION): Patients view HOPE-Genomics tool (containing educational content) over 15-20 minutes before their sequencing results are available. Patients also receive their genomics test results both from their clinician and from the HOPE-Genomics tool.

After completion of study intervention, patients are followed up at 2 weeks, 3 and 9 months after receiving genomic test results.

View Eligibility Criteria

Eligibility Criteria

Inclusion Criteria:

Are enrolled in City of Hope (COH) Institutional Review Board (IRB) 07047
Have a diagnosis of lung, breast, colorectal, pancreatic, ovarian or prostate cancer
Having somatic, germline or paired somatic/germline sequencing
Are fluent in English
Have an Eastern Cooperative Oncology Group (ECOG) performance status of 0-2
Are >= 18 years old

Exclusion Criteria:

Are unable to provide informed consent

Study is for people with:

Breast Cancer

Estimated Enrollment:

435

Study ID:

NCT04905082

Recruitment Status:

Recruiting

Sponsor:

City of Hope Medical Center

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There is 1 Location for this study

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City of Hope Medical Center
Duarte California, 91010, United States More Info
Stacy W. Gray
Contact
626-256-4673
[email protected]
Stacy W. Gray
Principal Investigator

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Study is for people with:

Breast Cancer

Estimated Enrollment:

435

Study ID:

NCT04905082

Recruitment Status:

Recruiting

Sponsor:


City of Hope Medical Center

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