Breast Cancer Clinical Trial
Novel Epothilone Plus Capecitabine Versus Capecitabine Alone in Patients With Advanced Breast Cancer
Summary
The purpose of this clinical research study is to learn if BMS-247550 added to the approved therapy of capecitabine is better than capecitabine alone in shrinking or slowing the growth of the cancer in women with metastatic breast cancer who are resistant to taxane and received anthracycline chemotherapy. The safety of this treatment will also be studied.
Eligibility Criteria
Patients must have received either 2 or 3 prior chemotherapy regimens including adjuvant or neoadjuvant therapy.
Prior treatment must have included both an anthracycline (i.e., doxorubicin or epirubicin) and a taxane (i.e., paclitaxel or docetaxel).
Patients must have received a minimum cumulative dose of anthracycline or must be resistant to an anthracycline.
Patients must be resistant to taxane therapy.
Patients may not have any history of brain and/or leptomeningeal metastases.
Patients may not have CTC Grade 2 or greater neuropathy (motor or sensory).
Patients may have not have had prior treatment with an epothilone and/or capecitabine (i.e., Xeloda)
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There is 1 Location for this study
Little Rock Arkansas, , United States
San Francisco California, , United States
Vallejo California, , United States
Denver Colorado, , United States
Hartford Connecticut, , United States
Washington District of Columbia, , United States
Orlando Florida, , United States
Baltimore Maryland, , United States
Burlington Massachusetts, , United States
Jackson Mississippi, , United States
Columbia Missouri, , United States
Kansas City Missouri, , United States
Saint Louis Missouri, , United States
Omaha Nebraska, , United States
Livingston New Jersey, , United States
New Brunswick New Jersey, , United States
Albuquerque New Mexico, , United States
New York New York, , United States
Columbus Ohio, , United States
Oklahoma City Oklahoma, , United States
Tulsa Oklahoma, , United States
Pittsburgh Pennsylvania, , United States
Columbia South Carolina, , United States
Greenville South Carolina, , United States
Knoxville Tennessee, , United States
Nashville Tennessee, , United States
Austin Texas, , United States
Houston Texas, , United States
Ogden Utah, , United States
Burlington Vermont, , United States
Tacoma Washington, , United States
Morgantown West Virginia, , United States
Capital Federal Buenos Aires, , Argentina
Haedo Buenos Aires, , Argentina
La Plata Buenos Aires, , Argentina
Mar Del Plata Buenos Aires, , Argentina
Pilar Buenos Aires, , Argentina
Quilmes Buenos Aires, , Argentina
Lanus BuenosAires, , Argentina
Rosario Santa Fe, , Argentina
Cordoba , , Argentina
Neuquen , , Argentina
Santa Fe , , Argentina
Edegem , , Belgium
Gent , , Belgium
Leuven , , Belgium
Liege , , Belgium
Fortaleza Ceara, , Brazil
Belo Horizonte Mina Gerais, , Brazil
Curitiba Parana, , Brazil
Porto Alegre Rio Grande Do Sul, , Brazil
Jau Sao Paulo, , Brazil
Santo Andre Sao Paulo, , Brazil
Sao Paulo - Sp Sao Paulo, , Brazil
Sao Paulo , , Brazil
Vancouver British Columbia, , Canada
Oshawa Ontario, , Canada
Toronto Ontario, , Canada
Montreal Quebec, , Canada
Beijing Beijing, , China
Guangzhou Guangdong, , China
Nanjing Jiangsu, , China
Jinan Shandong, , China
Beijing Shanghai, , China
Xi'An Shanxi, , China
Beijing , , China
Shanghai , , China
Angers , , France
Avignon Cedex 2 , , France
Bayonne , , France
Besancon , , France
Bobigny , , France
Bordeaux , , France
Clermont-Ferrand , , France
Lyon , , France
Nantes , , France
Nice , , France
Saint Brieuc Cedex , , France
Saint-Cloud Cedex , , France
St. Herblain Cedex , , France
Strasbourg Cedex , , France
Toulouse Cedex 3 , , France
Berlin , , Germany
Duisburg , , Germany
Erlangen , , Germany
Athens , , Greece
Thessaloniki , , Greece
Budapest , , Hungary
Debrecen , , Hungary
Gyor , , Hungary
Pecs , , Hungary
Brescia , , Italy
Candiolo (To) , , Italy
Forli , , Italy
San Giovanni Rotondo , , Italy
Incheon , , Korea, Republic of
Seoul , , Korea, Republic of
Nilai Negeri Sembilan, , Malaysia
Kuala Lumpur , , Malaysia
Acapulco Guerrero, , Mexico
Merida Yucatan, , Mexico
Chihuahua , , Mexico
Distrito Federal , , Mexico
San Luis Potosi , , Mexico
Lima , , Peru
Manila , , Philippines
Quezon City , , Philippines
Quezon , , Philippines
Gdansk , , Poland
Opole , , Poland
Barcelona , , Spain
Girona , , Spain
Madrid , , Spain
Valencia , , Spain
Zaragoza , , Spain
Gothenburg , , Sweden
Stockholm , , Sweden
Tainan , , Taiwan
Taipei , , Taiwan
Bangkok , , Thailand
Bristol Avon, , United Kingdom
Chelmsford Essex, , United Kingdom
London Greater London, , United Kingdom
Manchester Greater Manchester, , United Kingdom
Sheffield South Yorkshire, , United Kingdom
Guildford Surrey, , United Kingdom
Newcastle-Upon-Tyne Tyne And Wear, , United Kingdom
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