Breast Cancer Clinical Trial
Partial Breast Proton Therapy for Early Stage Breast Cancer
Summary
The purpose of this is to determine the efficacy and toxicity of proton therapy when used to deliver partial breast radiotherapy in patients with early stage breast cancer with low or intermediate risk factors.
Full Description
Radiation therapy delivered to the whole breast is standard treatment following tumor removal for patients with early stage breast cancer. In selected patients, delivering the radiation treatment to only the part of the breast involved by the tumor may be a viable alternative. This can decrease the amount of normal tissues exposed to irradiation, potentially decrease side-effects and shorten the treatment time. Proton beam can decrease the volume of normal tissues treated compared to standard forms of radiotherapy. This study will recruit patients with early stage breast cancer following surgical removal to undergo partial breast radiotherapy with proton beam and determine the recurrence rates and side-effects of treatment.
Eligibility Criteria
Inclusion Criteria:
Breast carcinoma
DCIS
Age 40 years or higher
Primary tumor 3 cm or less
Lumpectomy with clip placement
Axillary node sampling
Negative margins
Exclusion Criteria:
Distant metastasis
Multicentric disease
Prior radiation or chemotherapy
Active collagen vascular disease
Pregnant or lactating
BRCA mutation
Lymph nodes with more than microscopic tumor involvement
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There is 1 Location for this study
Loma Linda California, 92354, United States
Loma Linda California, 92354, United States
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