Reach for Health Study: Obesity-related Mechanisms and Mortality in Breast Cancer Survivors

Inclusion Criteria:

BMI at least 25.0 kg/m2
Diagnosed with Stage I, II, or III breast cancer within past 5 years
Treatment with total mastectomy or breast-sparing surgical removal of cancer with clear macroscopic margins, and axillary dissection, followed by adjuvant breast radiation
Not scheduled for or currently undergoing chemotherapy
Accessible geographically and by telephone
Able to communicate dietary and physical activity data via telephone
If taking statins, tamoxifen, or aromatase inhibitors; able and willing to remain on treatment for 6-month study period
Post-menopausal at diagnosis

Exclusion Criteria:

Preliminary bloodwork outside of specified ranges
Evidence of renal insufficiency, liver disease, or congestive heart failure
Currently taking corticosteroid pills or steroid hormone therapy (including vaginal estrogen creams)
Recent initiation (< 3 months ago) of thiazides or β-blockers
Taking insulin or other antidiabetic drug
Other primary or recurrent invasive cancer in past 10 years
Unable to commit to study requirements