Breast Cancer Clinical Trial

Reducing HIV Stigma for African American Women

Summary

African American women account for 66% of HIV infections in women in the U.S., AIDS is a leading cause of death for African American women, and African Americans have the lowest medication adherence rates compared to other groups in the U.S. One of the reasons for low medication adherence among African Americans is fear of stigma. HIV stigma has been linked to depression, psychological distress, poor quality of life, poor medication adherence and service utilization contributing to morbidity and mortality. Research has found that stigma is a moderator to poor adherence via depressive symptoms.

The current study is a randomized control trial with a time and attention control group to test the effectiveness of a stigma reduction intervention adapted for use with African American women. A total of 224 African American women will be recruited to participate in the study. Half of the women will be from Chicago, Illinois (112) and the other half will be from Birmingham, Alabama (112). A workshop will be held once a study site has recruited 28 women, half of the women will be in the intervention group (14) and the other half will be in the control group (14). Each study site will have 4 cohorts of 28 women.

The main aims of the current study are:

to determine the long-term effectiveness of the intervention to reduce stigma for African American women living with HIV in Chicago Illinois and Birmingham, Alabama
to examine whether stigma reduction due to the intervention is associated with improved physical health biomarkers (CD4+ T cell count, viral load), mediated by reduced psychological symptoms (depressive symptoms), improved engagement to care, and improved medication adherence
to explore whether stigma reduction due to the intervention is moderated by location (Chicago vs. Birmingham), transmission risk factor, time since diagnosis, and perceived social support

We expect that the multimedia workshop intervention will demonstrate effectiveness in reducing internalized stigma through an easily-disseminated method, and that it will have a positive impact on medication adherence and engagement in care for African American women living with HIV.

View Eligibility Criteria

Eligibility Criteria

Inclusion Criteria:

they are women who identify as having an African American racial/ethnic background
born in the U.S. (including women of Caribbean origin if born in the U.S.
speak and understand English as their primary language of communication outside the home
they are 18 years of age or older
have a documented HIV positive status (women are on antiretroviral treatment and women who are not on antiretroviral are eligible)
able to see and interact with a touchscreen computer in English.

Exclusion Criteria:

women who not self-identify as African American
women who are African born or born outside the United States
younger than 18 years of age
unable to provide informed consent
life expectancy less than 1 year per physician report
unable to see and interact with a touchscreen computer in English.

Study is for people with:

Breast Cancer

Estimated Enrollment:

240

Study ID:

NCT01893112

Recruitment Status:

Completed

Sponsor:

University of Washington

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There are 2 Locations for this study

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University of Alabama Birmingham
Birmingham Alabama, 35233, United States
Northwestern University (NU)
Chicago Illinois, 60611, United States

How clear is this clinincal trial information?

Study is for people with:

Breast Cancer

Estimated Enrollment:

240

Study ID:

NCT01893112

Recruitment Status:

Completed

Sponsor:


University of Washington

How clear is this clinincal trial information?

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