Breast Cancer Clinical Trial

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Study of Anastrozole +/- AZD8931 in Postmenopausal Women With Endocrine Therapy Naive Breast Cancer

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Summary

The main purpose of this study is to compare progression free survival in patients treated with AZD8931 given in combination with anastrozole versus anastrozole alone. The secondary objective is to investigate the safety and tolerability of AZD8931 given in combination with anastrozole.

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Eligibility Criteria

Inclusion Criteria:

Patients that have locally advanced or metastatic breast cancer. Lesions should not be amenable to surgery or radiation of curative intent
Hormone therapy-naive
Estimated life expectancy of more than 12 weeks

Exclusion Criteria:

Last dose of prior anti-cancer therapy received within 14 days (or longer if required)
Any eye injury or corneal surgery within 3 months prior to receiving first dose of study drug.
Currently receiving (and unwilling to discontinue) oestrogen replacement therapy. (last dose <7 days prior to randomisation)

Study is for people with:

Breast Cancer

Phase:

Phase 2

Estimated Enrollment:

482

Study ID:

NCT01151215

Recruitment Status:

Terminated

Sponsor:

AstraZeneca

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There is 1 Location for this study

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Research Site
Lake Success New York, , United States
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Belo Horizonte , , Brazil
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Goiânia , , Brazil
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Ijuí , , Brazil
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Porto Alegre , , Brazil
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Rio de Janeiro , , Brazil
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Sao Paulo , , Brazil
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São Paulo , , Brazil
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Vancouver British Columbia, , Canada
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Ottawa Ontario, , Canada
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Montreal Quebec, , Canada
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Brno , , Czech Republic
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Olomouc , , Czech Republic
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Praha 2 , , Czech Republic
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Praha 4 , , Czech Republic
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Helsinki , , Finland
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Tampere , , Finland
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Turku , , Finland
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Bangalore , , India
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Hyderabad , , India
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Mumbai , , India
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Pune , , India
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Trivandrum , , India
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Vellore , , India
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Niigata-shi , , Japan
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Osaka-shi , , Japan
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Ota-shi , , Japan
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Sapporo-shi , , Japan
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Seoul , , Korea, Republic of
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Durango , , Mexico
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Juchitan , , Mexico
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Merida , , Mexico
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Monterrey , , Mexico
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Callao , , Peru
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Lima , , Peru
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Piura , , Peru
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Iloilo City , , Philippines
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Lipa City , , Philippines
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Pasay City , , Philippines
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Quezon City , , Philippines
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Białystok , , Poland
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ElblÄ…g , , Poland
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Kraków , , Poland
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Warszawa , , Poland
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Kuzmolovsky , , Russian Federation
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Moscow , , Russian Federation
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Saint Petersburg , , Russian Federation
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Durban , , South Africa
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Pretoria , , South Africa
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Taipei , , Taiwan
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Bangkok , , Thailand
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Songkla , , Thailand
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Dnipropetrovsk , , Ukraine
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Lviv , , Ukraine
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Birmingham , , United Kingdom
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Bournemouth , , United Kingdom
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Coventry , , United Kingdom
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Leicester , , United Kingdom
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London , , United Kingdom
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Nottingham , , United Kingdom
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Surrey , , United Kingdom
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Wythenshawe, Manchester , , United Kingdom

How clear is this clinincal trial information?

Study is for people with:

Breast Cancer

Phase:

Phase 2

Estimated Enrollment:

482

Study ID:

NCT01151215

Recruitment Status:

Terminated

Sponsor:


AstraZeneca

How clear is this clinincal trial information?

Clinical Trial Resources

SurvivorNet’s Guide To Clinical Trials: What Are They And Are They Right for You?
Clinical Trials for Breast Cancer
Have You Been Diagnosed With Late-Stage Breast Cancer? Know That You Have Treatment Options.
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