Study of Chemotherapy-Induced Hair Changes and Alopecia, Skin Aging and Nail Changes in Women With Non-Metastatic Breast Cancer

Inclusion Criteria:

Women newly diagnosed with non-metastatic breast cancer (stage 0-III, any receptor type) at the time of starting chemotherapy (dd-AC-T, CMF, Newer Combination Regimens) or endocrine therapy (tamoxifen, anastrozole, letrozole, exemestane)
Women ≥ 18 years at the time of enrollment into the study
Able to communicate in English and participate in the informed consent process
Able to comply with the follow-up visits, assessments, answering questionnaires

Exclusion Criteria:

Metastatic breast cancer
Follow-up care/visits not scheduled at MSKCC
Any current alopecia especially due to an active scalp and/or hair disorder (e.g. alopecia areata), or a pre-existing condition with sequelae (e.g. scarring alopecia)
Currently active or uncontrolled medical condition [e.g. thyroid disorder, auto-immune connective tissue disease (e.g. SLE), BMT complications (GVHD)] or medication intake (e.g. HRT), affecting scalp hair
Prior systemic treatment for any malignancy
Active secondary cancer requiring cytotoxic chemotherapy
Planned (or a history of) radiation therapy to the head
Vulnerable populations [e.g. decisionally impaired (cognitive, psychiatric), terminally ill, prisoners], or patients who, in the opinion of the investigator have a condition that precludes their ability to provide an informed consent
Men

Volunteer Inclusion Criteria:

Post menopausal women, with menopausal status defined as (per self report):
Bilateral salpingo-oophorectomy independent of age
If natural menopause, age ≥ 50 with cessation of menses for at least 12 months
Or premenopausal women with premenopausal status defined as <53 years of age with no cessation of menses
Able to communicate in English and participate in the informed consent process
Able to comply with the baseline assessments and answering questionnaires
Women >/= 18 years at the time of enrollment into the study