Breast Cancer Clinical Trial

Study of NGM707 as Monotherapy and in Combination With Pembrolizumab in Advanced or Metastatic Solid Tumor Malignancies

Summary

Study of NGM707 as Monotherapy and in Combination with Pembrolizumab in Advanced or Metastatic Solid Tumor Malignancies

View Eligibility Criteria

Eligibility Criteria

Inclusion Criteria:

Histologically or cytologically documented locally advanced or metastatic solid tumor malignancy.
Progressed or was intolerant to all available therapies known to confer clinical benefit appropriate for their tumor type, and for which the patient was eligible and willing to receive, or refused SOC treatments that are perceived to have marginal clinical benefit.
Adequate bone marrow, kidney and liver function.
Performance status of 0 or 1.
Resolved acute effects of any prior therapy to baseline severity or CTCAE Grade 1 except for AEs not constituting a safety risk by Investigator judgement.

Exclusion Criteria:

Prior treatment targeting ILT2 and/or ILT4 or targeting HLA-G.

Study is for people with:

Breast Cancer

Phase:

Phase 1

Estimated Enrollment:

179

Study ID:

NCT04913337

Recruitment Status:

Recruiting

Sponsor:

NGM Biopharmaceuticals, Inc

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There are 17 Locations for this study

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University of Southern California
Los Angeles California, 90033, United States More Info
NGM Site 004
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Hoag Memorial Hospital Presbyterian
Newport Beach California, 92663, United States More Info
NGM Site 016
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UCLA Medical Center
Santa Monica California, 90404, United States More Info
NGM Site 010
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Georgetown University Medical Center
Washington District of Columbia, 20007, United States More Info
NGM Site 008
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Florida Cancer Specialists - Sarasota - SCRI
Sarasota Florida, 34232, United States More Info
NGM Site 009
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University of Maryland Greenebaum Cancer Center
Baltimore Maryland, 21201, United States More Info
NGM Site 007
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Dana-Farber Cancer Institute
Boston Massachusetts, 02215, United States More Info
NGM Site 014
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START Midwest, LLC
Grand Rapids Michigan, 49546, United States More Info
NGM Site 003
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Nebraska Cancer Specialists
Omaha Nebraska, 68130, United States More Info
NGM Site 012
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Prisma Health - Upstate
Greenville South Carolina, 29605, United States More Info
NGM Site 013
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University of Texas Southwestern Medical Center
Dallas Texas, 78701, United States More Info
NGM Site 006
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MD Anderson Cancer Center
Houston Texas, 77030, United States More Info
NGM Site 001
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NEXT Oncology
San Antonio Texas, 78229, United States More Info
NGM Site 002
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Seoul National University Hospital
Seoul , 03080, Korea, Republic of More Info
NGM Site 200
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Samsung Medical Center
Seoul , 06351, Korea, Republic of More Info
NGM Site 201
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China Medical University Hospital
Taichung , 40432, Taiwan More Info
NGM Site 252
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National Taiwan University Hospital
Taipei , 10022, Taiwan More Info
NGM Site 250
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How clear is this clinincal trial information?

Study is for people with:

Breast Cancer

Phase:

Phase 1

Estimated Enrollment:

179

Study ID:

NCT04913337

Recruitment Status:

Recruiting

Sponsor:


NGM Biopharmaceuticals, Inc

How clear is this clinincal trial information?

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