Breast Cancer Clinical Trial
Tangential Radiation Therapy Without Axillary Dissection in Breast Cancer
Summary
The purpose of this study is to evaluate whether treatment to the axilla (area under the arm) can be safely minimized by omitting axillary surgery and full axillary radiation therapy and replacing it with radiation therapy to the breast and lower axilla.
Full Description
Patients will have undergone conservative breast surgery without axillary dissection prior to enrollment in this study.
Patients will receive radiation therapy to the breast, including the lowest axillary lymph nodes, over a period of 6 1/2 weeks.
No radiation will be specifically directed toward the upper axilla or supraclavicular lymph nodes.
Patients will also receive 5 years of tamoxifen or another type of hormone therapy determined by the medical oncologist.
Follow-up visits will occur every 6 months and mammograms every 12 months.
Eligibility Criteria
Inclusion Criteria:
Patients must have clinical stage I or II breast cancer, clinically uninvolved axillary nodes.
Patients must be 55 years or older.
Patients must undergo total excision of the primary invasive tumor
Final pathologic margin status must be negative
Only estrogen receptor (ER) or progesterone receptor (PR) positive tumors will be permitted
Exclusion Criteria:
Prior history of malignancy, except for non-melanoma skin cancers and carcinoma in situ fo the cervix
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There is 1 Location for this study
Boston Massachusetts, 02115, United States
Boston Massachusetts, 02115, United States
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