Telerehabilitation Cognitive Impairments Following Chemotherapy Usability Study

At NJ Bioscience Center Healthy Volunteers

Female
Age 20 to 65;
Good or corrected hearing;
Good or corrected vision;
No motor or cognitive impairments;
English speakers;
Those with low propensity for simulation sickness (as determined by the Simulation Sickness Questionnaire [Kennedy et al, 1993]).
Either healthy or having had stage II or stage III breast cancer;
Montreal Cognitive Assessment (MoCA) Score 10-25 indicating mild to moderate impairment [Chapman 2016] or 26-30 indicating normal cognition;

EXCLUSION CRITERIA

Male;
Female participants younger than 20 or older than 65;
High propensity for simulation sickness (as determined by Simulation Sickness Questionnaire screening);
Those with severe visual neglect or legally blind;
Those with severe hearing loss or deafness;
Those with uncontrolled hypertension (>190/100 mmHg);
Those with severe cognitive impairment (MoCA score<10);
Current diagnosis of moderate-severe depression (Beck Depression Inventory II score of 17-63);
a history of psychiatric illness, defined as serious psychiatric illness such as bipolar mood disorder and schizophrenia, or requiring psychiatric hospitalization.
a history of or current substance abuse;
a previous head injury resulting in loss of consciousness;
a prior diagnosis of neurological illness;
a current or prior diagnosis of brain cancer;
non-English speakers;
Those unable to reliable participate in pre-study assessment due to any reason;
Those with co-morbidities limiting arm and neck motor function (ex. lymphedema, chronic pain, severe arthritis);
Less than 1 month post first chemotherapy regimen or starting chemotherapy during 16 weeks post screening (as chemotherapy during study participation is a confounding factor);
Those with Stage IV (metastatic) breast cancer will be excluded;
Those presenting with multiple cancers, such as breast and arm bone cancer, or breast and brain cancer;
Those who are unwilling to allow a home inspection to ascertain Internet quality, determine best placement for the experimental or sham systems, for installation and removal of the systems and necessary repairs.