Breast Cancer Clinical Trial

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Use of Trastuzumab to Induce Increased ER Expression in ER-negative/Low, Her-2/Neu Positive Breast Cancer

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Summary

The majority pf breast cancers present as ER-positive, many of which are able to be targeted with multiple hormonal therapies. Altering ER-negative tumors to increase ER expression has the potential to benefit patients by making hormonal therapies a therapeutic option and possibly improving their overall prognosis.

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Eligibility Criteria

Inclusion Criteria:

Women who have Her-2 positive and ER- negative or ER-low breast cancer that has not metastasized, or spread to other parts of the body, are eligible for the study.
Participants must have had either a core biopsy or incisional biopsy of their breast cancer, but not yet had definitive breast surgery, including lumpectomy or mastectomy.
Participants may not have had a BRCA mutation found on genetic testing.

Participants should have not yet received treatment for their breast cancer, including:

chemotherapy,
hormonal therapy,
trastuzumab.

Study is for people with:

Breast Cancer

Phase:

Phase 1

Estimated Enrollment:

1

Study ID:

NCT00726180

Recruitment Status:

Terminated

Sponsor:

University of Michigan Rogel Cancer Center

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There is 1 Location for this study

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University of Michigan Comprehensive Cancer Center
Ann Arbor Michigan, 48109, United States

How clear is this clinincal trial information?

Study is for people with:

Breast Cancer

Phase:

Phase 1

Estimated Enrollment:

1

Study ID:

NCT00726180

Recruitment Status:

Terminated

Sponsor:


University of Michigan Rogel Cancer Center

How clear is this clinincal trial information?

Clinical Trial Resources

SurvivorNet’s Guide To Clinical Trials: What Are They And Are They Right for You?
Clinical Trials for Breast Cancer
Have You Been Diagnosed With Late-Stage Breast Cancer? Know That You Have Treatment Options.
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