Breast Cancer Clinical Trial
Yoga for Aromatase Inhibitor-associated Joint Pain
Summary
The purpose of this study is to determine whether it might be practical and useful to investigate the effectiveness of yoga classes in relieving joint pain associated with the use of a class of medications known as aromatase inhibitors.
Full Description
The study uses a single-arm design. All study participants will be assigned to an intervention condition in which they participate in group Iyengar yoga classes for 90 minutes twice per week for 12 weeks (total of 24 classes). Study outcomes are assessed: 1) following recruitment but prior to the first yoga class; and 2) within two weeks post-intervention (follow-up). Additionally, a brief assessment of pain will be conducted four weeks and eight weeks after the start of yoga classes.
Eligibility Criteria
Inclusion Criteria:
Have been diagnosed with stage 0-III breast cancer
Have completed local and/or adjuvant breast cancer therapy (with the exception of hormonal therapy) at least one month previously
Are post-menopausal defined as defined as no menses in the past 12 months
Are currently prescribed an aromatase inhibitor (AI) medication (anastrozole, letrozole, or exemestane) by a Moffitt-affiliated physician
Report joint pain that started or worsened after initiation of AI medication
Report worst pain score > 4 in the preceding week on an 11-point (0-10) numeric rating scale
Exclusion Criteria:
Have been diagnosed with another form of cancer (except nonmelanoma skin cancer) in the last five years
Have uncontrolled cardiac disease, pulmonary disease, or infectious disease
Have physical symptoms or conditions that could make yoga unsafe (i.e., neck injuries, dizziness, shortness of breath, chest pain, or severe nausea)
Have a body mass index (BMI) > 40 kg/m^2 (based on difficulties severly obese individuals may have with engaging in Iyengar yoga poses)
Have joint pain attributed to inflammatory arthritic conditions (i.e., rheumatoid arthritis, gout, pseudo-gout) per medical record or patient history
Had surgery within the past 3 months
Had injections of medication within the last 3 months to joint(s) currently painful
Are currently using corticosteroids or opioid medications
Are currently attending yoga classes
Do not speak or read standard English
Are scheduled or are planning to discontinue AI medication in the next 16 weeks
Do not have sufficient access to the Internet to complete study assessments
Check Your Eligibility
Let’s see if you might be eligible for this study.
What is your age and gender ?
There is 1 Location for this study
Tampa Florida, 33612, United States
How clear is this clinincal trial information?
Please confirm you are a US based health care provider:
Yes, I am a health care Provider No, I am not a health care providerSign Up Now.
Take Control of Your Disease Journey.
Sign up now for expert patient guides, personalized treatment options, and cutting-edge insights that can help you push for the best care plan.