Chronic Lymphocytic Leukemia Clinical Trial
informCLLâ„¢: A Disease Registry for Patients With Chronic Lymphocytic Leukemia
Summary
The study is designed as a multicenter, prospective, observational registry of leukemia-cll/" >CLL/SLL patients who are initiating approved oral kinase inhibitors, BCL-2 inhibitors or other approved anti-CLL therapies/regimens. The study will characterize treatment patterns and their association with patient characteristics, healthcare resource utilization, and clinical outcomes, as well as patient-reported outcome (PRO) measures.
Full Description
This multicenter, prospective, observational registry of CLL patients is designed to characterize and describe treatment patterns for those initiating treatment with approved oral kinase inhibitors and other approved anti-CLL therapies/ regimens. The registry will provide information on regimens used to treat first-line and later lines of CLL as well as the sequencing of treatment regimens. The registry will also evaluate the association of these treatment patterns with patient characteristics, healthcare resource utilization, and functional outcomes including patient-reported HRQoL. These data will provide information to physicians that may help guide clinical practice and appropriate use of therapies, and will also provide information on HRQoL and healthcare resource utilization that will be of interest to healthcare decision makers.
Eligibility Criteria
Inclusion Criteria:
Age of at least 18 years
Clinical diagnosis of CLL/SLL that meets published diagnostic criteria (Hallek 2008)
Initiating anti-CLL/SLL treatment regimen (excluding clinical trials) within ±45 days of enrollment
Availability of documentation of previous CLL/SLL treatment and duration of response in the patient's medical records if patient has received prior line(s) of treatment (i.e. NOT treatment naïve)
Willing and able to provide informed consent
Willing and able to complete PRO instrument
Willing and able to provide information on patient survey questionnaire
Willing and able to provide a blood sample at time of enrollment prior to receiving treatment, as possible
Exclusion Criteria:
Diagnosis of B-cell malignancies other than CLL/SLL
Estimated life expectancy <6 months
Currently receiving treatment in an interventional clinical trial at time of entry into this study * Note- Exceptions: 1) Patients may enroll in interventional clinical trials for indications other than CLL/SLL, 2) The interventional clinical trial treatment is not the treatment used for meeting Inclusion Criteria #2 (or "Index Treatment"), 3) Patients may enroll in an interventional clinical trial indicated for CLL/SLL as later line of treatment after discontinuing the Index Treatment
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There are 188 Locations for this study
Huntsville Alabama, 35805, United States
Muscle Shoals Alabama, 35661, United States
Glendale Arizona, 85308, United States
Phoenix Arizona, 85016, United States
Phoenix Arizona, 85027, United States
Tempe Arizona, 85284, United States
Fort Smith Arkansas, 72903, United States
Hot Springs Arkansas, 71913, United States
Jonesboro Arkansas, 72401, United States
Little Rock Arkansas, 72205, United States
Concord California, 94520, United States
Oceanside California, 92056, United States
Saint Helena California, 94574, United States
Santa Barbara California, 93105, United States
Santa Rosa California, 95403, United States
Solvang California, 93463, United States
Vallejo California, 94589, United States
Aurora Colorado, 80012, United States
Boulder Colorado, 80303, United States
Colorado Springs Colorado, 80907, United States
Denver Colorado, 80218, United States
Denver Colorado, 80220, United States
Lakewood Colorado, 80228, United States
Littleton Colorado, 80120, United States
Lone Tree Colorado, 80124, United States
Longmont Colorado, 80501, United States
Parker Colorado, 80138, United States
Pueblo Colorado, 81008, United States
Thornton Colorado, 80260, United States
Boynton Beach Florida, 33426, United States
Fort Lauderdale Florida, 33308, United States
Jacksonville Florida, 32082, United States
Jacksonville Florida, 32207, United States
Lakeland Florida, 33805, United States
Lakeland Florida, 33805, United States
Pensacola Florida, 32504, United States
Albany Georgia, 31701, United States
Augusta Georgia, 30912, United States
Brunswick Georgia, 31520, United States
Chicago Illinois, 60637, United States
Harvey Illinois, 60426, United States
Normal Illinois, 61761, United States
Peoria Illinois, 61615, United States
Rockford Illinois, 61108, United States
Skokie Illinois, 60077, United States
Tinley Park Illinois, 60487, United States
Anderson Indiana, 46016, United States
Indianapolis Indiana, 46219, United States
Indianapolis Indiana, 46260, United States
Lafayette Indiana, 47905, United States
South Bend Indiana, 46601, United States
Vincennes Indiana, 47591, United States
Ames Iowa, 50010, United States
Cedar Rapids Iowa, 52402, United States
Waterloo Iowa, 50702, United States
Topeka Kansas, 66606, United States
Mount Sterling Kentucky, 40353, United States
Paducah Kentucky, 42003, United States
Covington Louisiana, 70433, United States
New Orleans Louisiana, 70112, United States
Shreveport Louisiana, 71103, United States
Shreveport Louisiana, 71105, United States
Lewiston Maine, 04240, United States
Rockport Maine, 04856, United States
Scarborough Maine, 04074, United States
Cumberland Maryland, 21502, United States
Hagerstown Maryland, 21740, United States
Pittsfield Massachusetts, 01201, United States
Plymouth Massachusetts, 02360, United States
Kalamazoo Michigan, 49007, United States
Novi Michigan, 48374, United States
Saint Cloud Minnesota, 56303, United States
Jackson Mississippi, 39202, United States
Bolivar Missouri, 65613, United States
Jefferson City Missouri, 65109, United States
Saint Joseph Missouri, 64506, United States
Billings Montana, 59102, United States
Hastings Nebraska, 68901, United States
Lincoln Nebraska, 68506, United States
Lincoln Nebraska, 68510, United States
Omaha Nebraska, 68106, United States
Elizabeth New Jersey, 07207, United States
Englewood New Jersey, 07631, United States
Neptune New Jersey, 07753, United States
New Brunswick New Jersey, 08901, United States
Paramus New Jersey, 07652, United States
Williamstown New Jersey, 08360, United States
Farmington New Mexico, 87401, United States
Bronx New York, 10469, United States
East Hills New York, 11548, United States
East Setauket New York, 11733, United States
East Syracuse New York, 13057, United States
Glens Falls New York, 12801, United States
Manhasset New York, 11030, United States
Mount Kisco New York, 10549, United States
New York New York, 10016, United States
Nyack New York, 10960, United States
Syracuse New York, 13210, United States
White Plains New York, 10601, United States
Williamsville New York, 14221, United States
Cary North Carolina, 27518, United States
Charlotte North Carolina, 28204, United States
Greenville North Carolina, 27834, United States
Morehead City North Carolina, 28557, United States
Cleveland Ohio, 44195, United States
Columbus Ohio, 43219, United States
Middletown Ohio, 45005, United States
Toledo Ohio, 43623, United States
Youngstown Ohio, 44501, United States
Oklahoma City Oklahoma, 73120, United States
Eugene Oregon, 97401, United States
Medford Oregon, 97504, United States
Medford Oregon, 97504, United States
Portland Oregon, 97213, United States
Portland Oregon, 97225, United States
Portland Oregon, 97227, United States
Springfield Oregon, 97477, United States
Tualatin Oregon, 97062, United States
Lancaster Pennsylvania, 17605, United States
Monroeville Pennsylvania, 15232, United States
Philadelphia Pennsylvania, 19141, United States
Scranton Pennsylvania, 18510, United States
Williamsport Pennsylvania, 17701, United States
York Pennsylvania, 17403, United States
Charleston South Carolina, 29406, United States
Easley South Carolina, 29640, United States
Greenville South Carolina, 29605, United States
Greenville South Carolina, 29605, United States
Greenville South Carolina, 29615, United States
Greer South Carolina, 29650, United States
Hilton Head Island South Carolina, 29926, United States
Rock Hill South Carolina, 29732, United States
Seneca South Carolina, 29672, United States
Spartanburg South Carolina, 29303, United States
Spartanburg South Carolina, 29307, United States
Watertown South Dakota, 57201, United States
Cookeville Tennessee, 38501, United States
Jackson Tennessee, 38301, United States
Nashville Tennessee, 37208, United States
Nashville Tennessee, 37232, United States
Abilene Texas, 79601, United States
Abilene Texas, 79606, United States
Allen Texas, 75013, United States
Amarillo Texas, 79106, United States
Arlington Texas, 76012, United States
Arlington Texas, 76014, United States
Austin Texas, 78705, United States
Austin Texas, 78731, United States
Austin Texas, 78745, United States
Beaumont Texas, 77701, United States
Beaumont Texas, 77702, United States
Bedford Texas, 76022, United States
Carrollton Texas, 75010, United States
Dallas Texas, 75231, United States
Dallas Texas, 75246, United States
El Paso Texas, 79902, United States
El Paso Texas, 79915, United States
El Paso Texas, 79939, United States
Flower Mound Texas, 75028, United States
Grapevine Texas, 76051, United States
Harlingen Texas, 78550, United States
Longview Texas, 75601, United States
McAllen Texas, 78503, United States
McKinney Texas, 75071, United States
Mesquite Texas, 75150, United States
Midland Texas, 79701, United States
Odessa Texas, 79761, United States
Paris Texas, 75460, United States
Plano Texas, 75075, United States
Plano Texas, 75093, United States
Rockwall Texas, 75032, United States
San Antonio Texas, 78212, United States
San Antonio Texas, 78217, United States
San Antonio Texas, 78258, United States
Sherman Texas, 75090, United States
Sugar Land Texas, 77479, United States
Tyler Texas, 75701, United States
Tyler Texas, 75702, United States
Waco Texas, 76712, United States
Waco Texas, 76712, United States
Webster Texas, 77598, United States
Weslaco Texas, 78596, United States
Newport News Virginia, 23601, United States
Winchester Virginia, 22601, United States
Everett Washington, 98201, United States
Seattle Washington, 98104, United States
Tacoma Washington, 98405, United States
Vancouver Washington, 98684, United States
Walla Walla Washington, 99362, United States
Yakima Washington, 98902, United States
Green Bay Wisconsin, 54301, United States
Waukesha Wisconsin, 53188, United States
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