Chronic Lymphocytic Leukemia Clinical Trial
Open-label Extension Study of Navitoclax in Subjects With Chronic Lymphocytic Leukemia (CLL)
Summary
Open-label extension study of navitoclax in subjects with leukemia-cll/" >chronic lymphocytic leukemia (CLL).
Full Description
This is an open-label extension study of navitoclax in subjects with chronic lymphocytic leukemia (CLL).
Eligibility Criteria
Inclusion Criteria:
The subject has been dosing in Arm C of the ABT4710n study, has not discontinued for any reason prior to study closure and the investigator believes that continued treatment with navitoclax is in the best interest of the subject
The subject must meet defined hematology and coagulation lab criteria as specified in the protocol
The subject must meet defined chemistry criteria as specified in the protocol
Women of childbearing potential and men must agree to use adequate contraception (as per protocol) prior to study entry, for the duration of study participation and up to 90 days following completion of therapy
The subject is capable of understanding and complying with parameters as outlined in the protocol and able to sign the Informed Consent Form
Exclusion Criteria:
The subject discontinued navitoclax administration in Arm C of the ABT4710n study for reasons of disease progression, Adverse Event toxicity, withdrawal of consent or Investigator decision prior to study completion.
The subject has any medical condition which in the opinion of the investigator places the subject at an unacceptably high risk for toxicities.
The subject is a lactating or pregnant female.
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There are 15 Locations for this study
La Jolla California, 92093, United States
Los Angeles California, 90095, United States
Pleasant Hill California, 94523, United States
Santa Maria California, 93454, United States
Bethesda Maryland, 20817, United States
Coburg , 3058, Australia
Greenslopes , 4120, Australia
Afula , 18101, Israel
Rechovot , 76100, Israel
Gdansk , 80-95, Poland
Ivano-Frankivsk , 76008, Ukraine
Khmelnitsky , 29000, Ukraine
Kyiv , 03115, Ukraine
Lviv , 79044, Ukraine
Poltava , 36024, Ukraine
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