Chronic Lymphocytic Leukemia Clinical Trial

Open-label Extension Study of Navitoclax in Subjects With Chronic Lymphocytic Leukemia (CLL)

Summary

Open-label extension study of navitoclax in subjects with leukemia-cll/" >chronic lymphocytic leukemia (CLL).

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Full Description

This is an open-label extension study of navitoclax in subjects with chronic lymphocytic leukemia (CLL).

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Eligibility Criteria

Inclusion Criteria:

The subject has been dosing in Arm C of the ABT4710n study, has not discontinued for any reason prior to study closure and the investigator believes that continued treatment with navitoclax is in the best interest of the subject
The subject must meet defined hematology and coagulation lab criteria as specified in the protocol
The subject must meet defined chemistry criteria as specified in the protocol
Women of childbearing potential and men must agree to use adequate contraception (as per protocol) prior to study entry, for the duration of study participation and up to 90 days following completion of therapy
The subject is capable of understanding and complying with parameters as outlined in the protocol and able to sign the Informed Consent Form

Exclusion Criteria:

The subject discontinued navitoclax administration in Arm C of the ABT4710n study for reasons of disease progression, Adverse Event toxicity, withdrawal of consent or Investigator decision prior to study completion.
The subject has any medical condition which in the opinion of the investigator places the subject at an unacceptably high risk for toxicities.
The subject is a lactating or pregnant female.

Study is for people with:

Chronic Lymphocytic Leukemia

Phase:

Phase 2

Estimated Enrollment:

17

Study ID:

NCT01557777

Recruitment Status:

Completed

Sponsor:

AbbVie (prior sponsor, Abbott)

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There are 15 Locations for this study

See Locations Near You

Site Reference ID/Investigator# 74036
La Jolla California, 92093, United States
Site Reference ID/Investigator# 74035
Los Angeles California, 90095, United States
Site Reference ID/Investigator# 74038
Pleasant Hill California, 94523, United States
Site Reference ID/Investigator# 74039
Santa Maria California, 93454, United States
Site Reference ID/Investigator# 74033
Bethesda Maryland, 20817, United States
Site Reference ID/Investigator# 79201
Coburg , 3058, Australia
Site Reference ID/Investigator# 78993
Greenslopes , 4120, Australia
Site Reference ID/Investigator# 77860
Afula , 18101, Israel
Site Reference ID/Investigator# 77637
Rechovot , 76100, Israel
Site Reference ID/Investigator# 77413
Gdansk , 80-95, Poland
Site Reference ID/Investigator# 79203
Ivano-Frankivsk , 76008, Ukraine
Site Reference ID/Investigator# 79205
Khmelnitsky , 29000, Ukraine
Site Reference ID/Investigator# 79202
Kyiv , 03115, Ukraine
Site Reference ID/Investigator# 79204
Lviv , 79044, Ukraine
Site Reference ID/Investigator# 79206
Poltava , 36024, Ukraine

How clear is this clinincal trial information?

Study is for people with:

Chronic Lymphocytic Leukemia

Phase:

Phase 2

Estimated Enrollment:

17

Study ID:

NCT01557777

Recruitment Status:

Completed

Sponsor:


AbbVie (prior sponsor, Abbott)

How clear is this clinincal trial information?

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