Colon Cancer Clinical Trial

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Imaging With [89Zr]Panitumumab-PET/MRI in Patients With Newly Diagnosed Colorectal Cancer

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Summary

This clinical study will investigate the utility of PET imaging with [89Zr]Panitumumab for imaging of EGFR expression in newly diagnosed colon cancer patients to assess lymph node involvement. If promising, this data will be used to design larger trials.

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Eligibility Criteria

Inclusion Criteria:

Be at least 19 years of age.
Diagnosis of colon cancer
Scheduled to undergo surgical resection

Exclusion Criteria:

Inability to provide informed consent
Pregnancy
Inability to lie still for the imaging study
Weight over 350 lbs., due to the scanner bore size
Contraindication for MRI study (e.g. non-removable metal implants or certain tattoos)
Inability to receive Omnipaque (iohexol) iodinated contrast
Inability to receive glucagon
Inability to receive Eovist (gadoxetate disodium) gadolinium based contrast agent
Allergy to contrast imaging agents
Finding or suspicion of distant metastases on CT

Study is for people with:

Colon Cancer

Phase:

Phase 1

Study ID:

NCT03764137

Recruitment Status:

Withdrawn

Sponsor:

University of Alabama at Birmingham

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There is 1 Location for this study

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UAB Advanced Imaging Facility
Birmingham Alabama, 35294, United States

How clear is this clinincal trial information?

Study is for people with:

Colon Cancer

Phase:

Phase 1

Study ID:

NCT03764137

Recruitment Status:

Withdrawn

Sponsor:


University of Alabama at Birmingham

How clear is this clinincal trial information?

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