Colon Cancer Clinical Trial
PET-MRI in Diagnosing Patients With Colon or Rectal Cancer
Summary
This pilot clinical trial studies positron emission tomography (PET)-magnetic resonance imaging (MRI) and PET-computed tomography (CT) as diagnostic imaging in patients with colon and/or rectal cancer. New diagnostic imaging procedures, such as PET-MRI, may help find and diagnose rectal cancer or recurrence of colorectal cancer
Full Description
PRIMARY OBJECTIVES:
I. To test the diagnostic performance of PET- MRI in the staging of preoperative high-grade rectal cancer patients, defined by T3 stage or higher or N1 stage or higher or presence of metastasis, that are referred to PET-CT and MRI.
II. To test the diagnostic performance of PET-MRI the follow up of colorectal cancer patients that are referred to PET-CT with or without a diagnostic MRI request by their physicians.
SECONDARY OBJECTIVES:
I. To test different attenuation correction MR sequences and novel diagnostic MR sequences.
OUTLINE:
Patients undergo fludeoxyglucose F 18 PET-CT and PET-MRI.
Eligibility Criteria
Inclusion Criteria:
Either having a T3 (the cancer has grown through the muscularis propria and into the outermost layers of the colon or rectum but not through them) or higher, node positivity or metastatic lesion in the context of rectal cancer or being studied for colorectal cancer follow up, independent of the renal function
PET-CT should be requested by a referring physician; in the case of having an MR requested as well, it will be reported from the MRI images generated in the PET-MRI
Stable physical medical conditions to undergo a MRI
Informed consent must be given and signed prior to study enrollment
Exclusion Criteria:
Refuse to give and/or sign the informed consent
Subjects who do not meet the above mentioned inclusion criteria
Subjects who have a pacemaker
Subjects who have a metallic prostheses either in the pelvis or in the abdomen that will interfere with the MR imaging of that anatomical area
Subjects who suffer from claustrophobia
Pregnant women
Cognitive impairment that affects the subject's ability to give consent
Check Your Eligibility
Let’s see if you might be eligible for this study.
What is your age and gender ?
There is 1 Location for this study
Cleveland Ohio, 44106, United States
How clear is this clinincal trial information?
Please confirm you are a US based health care provider:
Yes, I am a health care Provider No, I am not a health care providerSign Up Now.
Take Control of Your Disease Journey.
Sign up now for expert patient guides, personalized treatment options, and cutting-edge insights that can help you push for the best care plan.