Evaluate Esophageal Reinforcement With ACell MatriStem Surgical Matrix: A Degradable Biologic Scaffold Material

Inclusion Criteria:

Patient 18 years of age or older
Pathologically confirmed Gastric, Gastroesophageal Junction (GEJ) or Esophageal, adenocarcinoma at either MSKCC or a participating site (biopsy may be performed at other institutions but slides must be confirmed at MSKCC or a participating site, as is routine care at our institution)
Patient undergoing any resection requiring an anastomosis to the esophagus for curative intent. Including but not limited to esophagectomy or total gastrectomy.
Subject is willing to provide written informed consent
Subject is willing and able to comply with the follow-up regimen

Exclusion Criteria:

Pregnant or lactating women
Intraoperative evidence of metastatic or locally-unresectable disease
Patients with known sensitivity or allergy to porcine materials.
Patients undergoing any resection requiring an anastomosis to the esophagus for palliative intent.