Esophageal Cancer Clinical Trial

Influence of Nutrition and Sarcopenia on Esophageal Cancer Outcomes

Summary

Prospective multicenter longitudinal (observational) study recruiting from tertiary centers for the surgical management of esophageal cancer; Virginia Mason Medical Center (Seattle, USA) and St Mary's Hospital (Imperial College, London, UK). This is intended to be a pilot study.

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Full Description

Patients undergoing curative treatment for esophageal cancer will be recruited at the time of routine clinical assessment shortly following initial diagnosis and will undergo clinical and radiological evaluation at two study time points: (1) staging investigation (e.g. laparoscopy or endoscopy) and (2) definitive surgical resection. Study time points have been judiciously chosen to coincide with interventions that form part of patient's routine clinical care. It is intended that sampling will occur on the day of each intervention/surgery following a routine period of fasting.

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Eligibility Criteria

Inclusion Criteria:

- Patients with the following characteristics will be eligible for inclusion in this study: i. aged 18-90 years ii. newly diagnosed (prior to treatment) with esophageal and/or gastroesophageal junctional cancer (adeno- or squamous cell carcinoma) iii. planning to undergo curative treatment, including surgical resection with or without neoadjuvant therapy

Exclusion Criteria:

- Patients with the following characteristics will not be eligible for inclusion in this study: i. pregnant females ii. without malignant esophageal disease iii. inability or unwillingness to provided informed written consent

Study is for people with:

Esophageal Cancer

Estimated Enrollment:

1717

Study ID:

NCT06314516

Recruitment Status:

Completed

Sponsor:

Benaroya Research Institute

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There is 1 Location for this study

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Virginia Mason Medical Center
Seattle Washington, 98101, United States

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Study is for people with:

Esophageal Cancer

Estimated Enrollment:

1717

Study ID:

NCT06314516

Recruitment Status:

Completed

Sponsor:


Benaroya Research Institute

How clear is this clinincal trial information?

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