Heart Failure Clinical Trial

Clinical Trial Finder Heart Failure Trials

A Trial to Study Neladenoson Bialanate Over 20 Weeks in Patients With Chronic Heart Failure With Reduced Ejection Fraction

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Summary

The objective of the study is to find the optimal dose of once daily oral neladenoson bialanate (BAY 1067197) when given in addition to standard therapy for heart failure with reduced ejection fraction (HFrEF).

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Eligibility Criteria

Inclusion Criteria:

Men or women aged 18 years and older
Diagnosis of chronic heart failure (CHF), NYHA ( New York Heart Association ) class II-IV, LVEF ≤ 35% and elevated NT-proBNP

Exclusion Criteria:

Acute de-novo heart failure
Requirement of any intravenous (IV) treatments following 48 hours prior to randomization
Mechanical support (e.g. intra-aortic balloon pump, endotracheal intubation, mechanical ventilation, or any ventricular assist device)
Any cause of chronic heart failure other than ischemic cardiomyopathy and idiopathic dilated cardiomyopathy

Study is for people with:

Heart Failure

Phase:

Phase 2

Estimated Enrollment:

427

Study ID:

NCT02992288

Recruitment Status:

Completed

Sponsor:

Bayer

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There are 73 Locations for this study

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Southwest Florida Research
Naples Florida, 34102, United States
Henry Ford Health System
Detroit Michigan, 48202, United States
University of Mississippi Medical Center
Jackson Mississippi, 39216, United States
St. Louis Heart & Vascular, PC
Saint Louis Missouri, 63136, United States
Glacier View Research Institute-Cardiology
Kalispell Montana, 59901, United States
Stony Brook University Medical Center
Stony Brook New York, 11794, United States
St. Elizabeth Youngstown Hospital
Youngstown Ohio, 44501, United States
Tennessee Center for Clinical Trials
Tullahoma Tennessee, 37388, United States
East Texas Cardiology
Houston Texas, 77002, United States
AZ St-Jan Brugge Oostende AV
Brugge , 8000, Belgium
Grand Hôpital de Charleroi
Gilly , 6060, Belgium
AZ Delta
Roeselare , 8800, Belgium
AZ Turnhout
Turnhout , 2300, Belgium
Spec Hosp for Active Treatm in Cardiology Sv Georgi Pernik
Pernik , 2300, Bulgaria
Specialized Hospital for Actrive Treatm of Card - Pleven
Pleven , 5800, Bulgaria
NMTH Tzar Boris III
Sofia , 1233, Bulgaria
UMHAT Tsaritsa Joanna-ISUL EAD Sofia
Sofia , 1527, Bulgaria
Multiprofile Hospital for Active Treatment Sveta Sofia
Sofia , 1618, Bulgaria
MHAT Dr Stefan Cherkezov
Veliko Tarnovo , 5000, Bulgaria
Medizinische Hochschule Hannover (MHH)
Hannover Niedersachsen, 30625, Germany
Herz- und Diabeteszentrum Nordrhein-Westfalen (HDZ NRW)
Bad Oeynhausen Nordrhein-Westfalen, 32545, Germany
St.-Johannes-Hospital Dortmund
Dortmund Nordrhein-Westfalen, 44137, Germany
Kliniken Maria Hilf GmbH
Mönchengladbach Nordrhein-Westfalen, 41063, Germany
Klinikum der Stadt Ludwigshafen am Rhein gGmbH
Ludwigshafen Rheinland-Pfalz, 67063, Germany
Charité Campus Virchow-Klinikum (CVK)
Berlin , 13353, Germany
KAT General Hospital of Athens
Kifisia / Athens Attica, 14561, Greece
G. Gennimatas General State Hospital of Athens
Athens , 11527, Greece
Thriassio General Hospital of Elefsina
Elefsina , 19018, Greece
Konstantopoulio General Hospital of Nea Ionia - Agia Olga
Nea Ionia / Athens , 142 3, Greece
Hippokration General Hospital of Thessaloniki
Thessaloniki , 54642, Greece
Barzilai Medical Center
Ashkelon , 78306, Israel
Hillel Yaffe Medical Center
Hadera , 38101, Israel
Rambam Health Corporation
Haifa , 31096, Israel
Shaare Zedek Medical Center
Jerusalem , 91031, Israel
Hadassah University Hospital Mount Scopus
Jerusalem , , Israel
Tel-Aviv Sourasky Medical Center
Tel Aviv , 64239, Israel
Assaf Harofeh Medical Center
Zrifin , 60930, Israel
A.O.U. Policlinico Federico II Napoli
Napoli Campania, 80131, Italy
Fondazione Policlinico Universitario Agostino Gemelli
Roma Lazio, 00168, Italy
ASST Papa Giovanni XXIII
Bergamo Lombardia, 24127, Italy
ASST Spedali Civili di Brescia
Brescia Lombardia, 25123, Italy
IRCCS Centro Cardiologico Fondazione Monzino
Milano Lombardia, 20138, Italy
AUSL 8 Arezzo
Arezzo Toscana, 52040, Italy
Gunma University Hospital
Maebashi Gunma, 371-8, Japan
National Hospital Organization Takasaki General Medical C
Takasaki Gunma, 370-0, Japan
Hyogo Prefectural Amagasaki General Medical Center
Amagasaki Hyogo, 660-8, Japan
National hospital Organization Mito Medical Center
Higashiibaraki Ibaraki, 311-3, Japan
R.I.A.C Naha City Hospital
Naha Okinawa, 902-8, Japan
Kishiwada Tokushukai Hospital
Kishiwada Osaka, 596-8, Japan
Takatsuki Red Cross Hospital
Takatsuki Osaka, 569-1, Japan
Minamino Cardiovascular Hospital
Hachioji Tokyo, 192-0, Japan
Nihon University Itabashi Hospital
Itabashi-ku Tokyo, 173-8, Japan
Tokyo Women's Medical University Hospital
Shinjuku-ku Tokyo, 162-8, Japan
Hiroshima University Hospital
Hiroshima , 734-8, Japan
Okayama Rosai Hospital
Okayama , 702-8, Japan
Osaka General Medical Center
Osaka , 558-8, Japan
Toyama Prefectural Central Hospital
Toyama , 930-8, Japan
Onze Lieve Vrouwe Gasthuis
Amsterdam , 1091 , Netherlands
Ziekenhuis Rijnstate
Arnhem , 6815 , Netherlands
Universitair Medisch Centrum Groningen
Groningen , 9700 , Netherlands
Erasmus Medisch Centrum
Rotterdam , 3015 , Netherlands
KLIMED Marek Klimkiewicz
Bialystok , 15-77, Poland
CLINICAL MEDICAL RESEARCH Sp. z o. o.
Katowice , 40-15, Poland
Szpital Specjalistyczny im. J. Dietla
Krakow , 31-12, Poland
Nzoz Salus
Lodz , 91-30, Poland
Szpital Kliniczny Przemienienia Panskiego
Poznan , 61-84, Poland
Twoja Przychodnia - Szczecinskie Centrum Medyczne
Szczecin , 71-43, Poland
IV Wojskowy Szpital Kliniczny z Poliklinika, SPZOZ
Wroclaw , 50-98, Poland
Hospital Clínico Universitario de Santiago de Compostela
Santiago de Compostela A Coruña, 15706, Spain
Hospital Universitario "Virgen de la Arrixaca"
El Palmar Murcia, 30120, Spain
Complejo Hospitalario Universitario A Coruña
A Coruña , 15006, Spain
Hospital General Universitario Gregorio Marañón
Madrid , 28007, Spain
Hospital Clínico Universitario San Carlos
Madrid , 28040, Spain
Hospital Clínico Universitario de Valencia
Valencia , 46010, Spain
Hospital Universitari i Politècnic La Fe
Valencia , 46026, Spain
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How clear is this clinincal trial information?

Study is for people with:

Heart Failure

Phase:

Phase 2

Estimated Enrollment:

427

Study ID:

NCT02992288

Recruitment Status:

Completed

Sponsor:


Bayer

How clear is this clinincal trial information?

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