Heart Failure Clinical Trial

Beta-Blockers in Heart Failure: Pharmacy-level Intervention Comparison

Summary

The overall objective of the proposed pilot study is to begin evaluation of two methods for promoting adherence to guidelines for beta-blocker therapy in heart failure. The design includes site level baseline measurement, feedback, remeasurement after six months, and randomized (by site) comparison samples. The setting is VA sites, with intervention directed at the pharmacy.

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Full Description

Current evidence-based guidelines in VA recommend one of three beta-blockers (carvedilol, metoprolol succinate, or bisoprolol) that have been shown to reduce mortality in heart failure patients with systolic dysfunction, with recommended target doses. However, Pharmacy Benefits Management (PBM) data indicate that prescribing for beta-blockers in heart failure patients that is not in accordance with guidelines is substantial, both in terms of the agent selected and the dose. Sites will be recruited and randomized to two different intensities of intervention to promote adherence to guidelines.

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Eligibility Criteria

Inclusion Criteria:

VA sites
Males and females

Exclusion Criteria:

none

Study is for people with:

Heart Failure

Estimated Enrollment:

220

Study ID:

NCT01002456

Recruitment Status:

Completed

Sponsor:

US Department of Veterans Affairs

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There is 1 Location for this study

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Edward Hines Jr. VA Hospital, Hines, IL
Hines Illinois, 60141, United States

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Study is for people with:

Heart Failure

Estimated Enrollment:

220

Study ID:

NCT01002456

Recruitment Status:

Completed

Sponsor:


US Department of Veterans Affairs

How clear is this clinincal trial information?

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