Destination Therapy Post Approval Study

Inclusion Criteria:

Patient or legally authorized representative provides written authorization and/or consent per institution and geographical requirements
Patient is intended to receive or be treated with a HeartWare HVAD System for use as destination therapy
Patient is consented prior to the HVAD implant procedure

Exclusion Criteria:

Patient who is, or is expected to be inaccessible for follow-up
Patient with exclusion criteria required by local law
Patient is currently enrolled in or plans to enroll in any concurrent drug and/or device study that may confound results (i.e., no required intervention that could affect interpretation of all-around product safety and or effectiveness)
Patient less than 18 years of age.
Patient with previous support by long-term mechanical circulatory support (MCS), not including temporary mechanical circulatory support.