Heart Failure Clinical Trial

Rapid Emergency Department Heart Failure Outpatient Trial (REDHOT II)

Summary

The purpose of this study is to test whether physicians can make more informed treatment, admission, and discharge decisions related to patient care by having serial Triage® BNP test results available to assess disease severity, while patients are being treated for HF in the Emergency Department and/or during their admission. This is believed to lead to a better outcome as well as more efficient and cost-effective treatment.

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Full Description

This is a patient-randomized clinical study consisting of patients who present to the ED requiring treatment and/or admission for HF. At each site, patients will be randomized into either a control arm or an experimental arm. Serial blood samples will be collected from all patients throughout their stay in the ED and the hospital. In the experimental arm, the Triage® BNP test will be performed on all blood samples collected and each BNP result will be made available to the attending physicians immediately. In the control arm, blood samples will not be analyzed on-site for BNP but instead sent directly to Biosite Inc. for testing.A comparison will be made between the control and experimental arms of the study to determine if there are any significant differences in length of stay, re-hospitalizations, all cause mortality, BNP levels, quality of life, and costs to treat patients.

View Eligibility Criteria

Eligibility Criteria

Inclusion Criteria:

Age 18 and older Patient needs treatment for HF

Exclusion Criteria:

Current MI or ACS with ST deviation of 1 mm or greater Renal failure requiring dialysis Undergone hemodialysis within the last month Enrollment (Baseline) Triage® BNP concentration = 100 pg/ml or less Enrolled in any other drug trial or receiving an experimental treatment for HF.

Study is for people with:

Heart Failure

Estimated Enrollment:

630

Study ID:

NCT00206843

Recruitment Status:

Completed

Sponsor:

Biosite

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There are 10 Locations for this study

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Chandler Regional Hospital
Chandler Arizona, 85224, United States
University of California, San Diego MedicalCenter
San Diego California, 92103, United States
Detroit Receiving Hospital/Wayne State University
Detroit Michigan, 48201, United States
Sinai Grace Hospital/Wayne State
Detroit Michigan, 48235, United States
Beaumont Hospital, Troy
Troy Michigan, 48085, United States
New York Methodist Hospital
Brooklyn New York, 11215, United States
Stony Brook University Hospital
Stony Brook New York, 11794, United States
Duke University Hospital
Durham North Carolina, 27710, United States
Wake Forest University Baptist Medical Center
Winston-Salem North Carolina, 27157, United States
Hospital of the University of Pennsylvania
Philadelphia Pennsylvania, 19104, United States

How clear is this clinincal trial information?

Study is for people with:

Heart Failure

Estimated Enrollment:

630

Study ID:

NCT00206843

Recruitment Status:

Completed

Sponsor:


Biosite

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