Kidney Cancer Clinical Trial
Disease Burden and Biology Using Tumor Cell Free DNA in Metastatic Kidney Cancer
Summary
This study will assess whether DNA released by kidney cancer into the blood stream and urine of patients can be used to monitor tumor burden and tumor response to treatment in patients receiving immunotherapy
Full Description
Primary Objective:
- Evaluate tumor cell free (cf)DNA as a dynamic marker of response to immuno-oncology (IO) therapy
Exploratory Objective:
- Collect data on somatic mutations in cfDNA to gain insight into the biology of IO-responders and -non-responders
Eligibility Criteria
Inclusion Criteria:
Renal Cell Carcinoma with clear cell component
Stage IV
Receiving IO-containing regimen
Measurable disease per RECIST 1.1
Exclusion Criteria:
Active cancer (exclusion criteria only for healthy patient cohort)
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There are 3 Locations for this study
Nashville Tennessee, 37212, United States More Info
Principal Investigator
Nashville Tennessee, 37232, United States More Info
Principal Investigator
Houston Texas, 77030, United States More Info
Principal Investigator
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