Kidney Cancer Clinical Trial

Preop Laxatives in Robotic Urologic Surgery

Summary

Minimally-invasive surgery, either laparoscopic or robotic, is commonly used in urology. Several urologic procedures including prostatectomy, radical nephrectomy, and partial nephrectomy are now commonly performed robotically. Patients undergoing these procedures often have delayed return of bowel function and persistent gastrointestinal symptoms including nausea/vomiting, abdominal distension, and bloating for several days to weeks after surgery. Postoperative stool softeners and laxatives are routinely used in an effort to minimize these symptoms, with varying degrees of success. The aim of this study will be to evaluate whether the use of a preoperative osmotic laxative will be beneficial in improving recovery of bowel function and alleviating postoperative gastrointestinal complaints in patients undergoing these procedures. Patients will be randomized to either receive or not receive three days of polyethylene glycol (PEG, also known as MiraLAX) on the three days before surgery. Patients in both groups will receive the same postoperative bowel regimen including scheduled PEG both in the hospital and upon discharge until first bowel movement. Patients will be given a questionnaire and diary to record their postoperative gastrointestinal symptoms and time to first bowel movement. These questionnaires and diaries will then be analyzed to determine differences in time to first bowel movement and gastrointestinal complaints during their recovery from surgery.

View Eligibility Criteria

Eligibility Criteria

Inclusion criteria:

-Patients 30 years or older undergoing robotic-assisted laparoscopic radical prostatectomy, transperitoneal radical nephrectomy, or transperitoneal partial nephrectomy

Exclusion criteria:

Patients under 30 years old
Patients with a contraindication to receiving polyethylene glycol or other forms of laxatives
People who regularly take Miralax
Patients undergoing retroperitoneal radical or partial nephrectomy
Patients with severe ulcerative colitis or Crohn's disease
Patients with intestinal diversions (colostomy, ileostomy)
Patients with prior abdominal or pelvic radiation
Patients who will not follow up with UIHC postoperatively
Patients who are incarcerated

Study is for people with:

Kidney Cancer

Phase:

Phase 4

Estimated Enrollment:

240

Study ID:

NCT05805436

Recruitment Status:

Recruiting

Sponsor:

Chad R. Tracy

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There is 1 Location for this study

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University of Iowa Hospitals & Clinics
Iowa City Iowa, 52242, United States More Info
Chad Tracy, MD
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How clear is this clinincal trial information?

Study is for people with:

Kidney Cancer

Phase:

Phase 4

Estimated Enrollment:

240

Study ID:

NCT05805436

Recruitment Status:

Recruiting

Sponsor:


Chad R. Tracy

How clear is this clinincal trial information?

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