Kidney Cancer Clinical Trial

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Study Evaluating Interferon And CCI-779 In Advanced Renal Cell Carcinoma

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Summary

The primary objective of this study is efficacy. The primary efficacy endpoint of this study is a comparison of the overall survival of subjects treated with CCI-779 [Temsirolimus], administered intravenously [IV] once weekly and the combination of CCI-779, administered IV once weekly with Interferon Alfa [IFN alfa] subcutaneously [SC] three times per week [TIW], compared with the overall survival of subjects treated with IFN alfa (SC TIW) alone, in poor-prognosis subjects with advanced RCC.

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Eligibility Criteria

Inclusion Criteria:

This study will be conducted in subjects with histologically confirmed, advanced (stage IV or recurrent disease) RCC who have not received prior systemic therapy for their disease,

Exclusion Criteria:

Subjects with central nervous system (CNS) metastases
Prior anticancer therapy for RCC
Prior investigational therapy/agents within 4 weeks of randomization

Study is for people with:

Kidney Cancer

Phase:

Phase 3

Estimated Enrollment:

626

Study ID:

NCT00065468

Recruitment Status:

Completed

Sponsor:

Pfizer

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There are 138 Locations for this study

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Pfizer Investigational Site
Little Rock Arkansas, 72205, United States
Pfizer Investigational Site
La Verne California, 91750, United States
Pfizer Investigational Site
Los Angeles California, 90024, United States
Pfizer Investigational Site
San Diego California, 92123, United States
Pfizer Investigational Site
San Francisco California, 94115, United States
Pfizer Investigational Site
Waterbury Connecticut, 06708, United States
Pfizer Investigational Site
Boca Raton Florida, 33428, United States
Pfizer Investigational Site
Miami Florida, 33136, United States
Pfizer Investigational Site
Chicago Illinois, 60612, United States
Pfizer Investigational Site
Urbana Illinois, 61801, United States
Pfizer Investigational Site
Indianapolis Indiana, 46303, United States
Pfizer Investigational Site
South Bend Indiana, 46601, United States
Pfizer Investigational Site
Terre Haute Indiana, 47802, United States
Pfizer Investigational Site
Kansas City Kansas, 66160, United States
Pfizer Investigational Site
Louisville Kentucky, 40202, United States
Pfizer Investigational Site
New Orleans Louisiana, 70121, United States
Pfizer Investigational Site
Baltimore Maryland, 21231, United States
Pfizer Investigational Site
Boston Massachusetts, 02215, United States
Pfizer Investigational Site
Ann Arbor Michigan, 48109, United States
Pfizer Investigational Site
Detroit Michigan, 48202, United States
Pfizer Investigational Site
Kansas City Missouri, 64131, United States
Pfizer Investigational Site
St. Louis Missouri, 63110, United States
Pfizer Investigational Site
Billings Montana, 59101, United States
Pfizer Investigational Site
Great Falls Montana, 59405, United States
Pfizer Investigational Site
Lebanon New Hampshire, 03766, United States
Pfizer Investigational Site
East Orange New Jersey, 07018, United States
Pfizer Investigational Site
Morristown New Jersey, 07960, United States
Pfizer Investigational Site
Bronx New York, 10466, United States
Pfizer Investigational Site
New York New York, 10021, United States
Pfizer Investigational Site
Rochester New York, 14642, United States
Pfizer Investigational Site
Valhalla New York, 10595, United States
Pfizer Investigational Site
Durham North Carolina, 27710, United States
Pfizer Investigational Site
Hickory North Carolina, 28602, United States
Pfizer Investigational Site
Cleveland Ohio, 44195, United States
Pfizer Investigational Site
Oklahoma City Oklahoma, 73104, United States
Pfizer Investigational Site
Portland Oregon, 97213, United States
Pfizer Investigational Site
Hershey Pennsylvania, 17033, United States
Pfizer Investigational Site
Philadelphia Pennsylvania, 19111, United States
Pfizer Investigational Site
Pittsburgh Pennsylvania, 15213, United States
Pfizer Investigational Site
Charleston South Carolina, 29414, United States
Pfizer Investigational Site
Knoxville Tennessee, 37920, United States
Pfizer Investigational Site
Memphis Tennessee, 38120, United States
Pfizer Investigational Site
Nashville Tennessee, 37232, United States
Pfizer Investigational Site
Houston Texas, 77030, United States
Pfizer Investigational Site
Salt Lake City Utah, 84112, United States
Pfizer Investigational Site
Richmond Virginia, 23249, United States
Pfizer Investigational Site
Seattle Washington, 98101, United States
Pfizer Investigational Site
Seattle Washington, 98109, United States
Pfizer Investigational Site
Buenos Aires, , Argentina
Pfizer Investigational Site
San Miguel de Tucuman Tucuman, 4000, Argentina
Pfizer Investigational Site
Buenos Aires , C1426, Argentina
Pfizer Investigational Site
Cordoba , 5000, Argentina
Pfizer Investigational Site
Mendoza , , Argentina
Pfizer Investigational Site
Quilmes , , Argentina
Pfizer Investigational Site
Kogarah New South Wales, 2217, Australia
Pfizer Investigational Site
Newcastle New South Wales, , Australia
Pfizer Investigational Site
Westmead New South Wales, 2145, Australia
Pfizer Investigational Site
Adelaide South Australia, 5000, Australia
Pfizer Investigational Site
Footscray Victoria, 3012, Australia
Pfizer Investigational Site
Heidelberg Victoria, 3084, Australia
Pfizer Investigational Site
Melbourne Victoria, 3050, Australia
Pfizer Investigational Site
Edmonton Alberta, T6G 1, Canada
Pfizer Investigational Site
Kelowna British Columbia, V1Y 5, Canada
Pfizer Investigational Site
Vancouver British Columbia, V5Z 3, Canada
Pfizer Investigational Site
Winnipeg Manitoba, R3E 0, Canada
Pfizer Investigational Site
Halifax Nova Scotia, B3H 1, Canada
Pfizer Investigational Site
London Ontario, N6A 4, Canada
Pfizer Investigational Site
Newmarket Ontario, L3Y 2, Canada
Pfizer Investigational Site
Ottawa Ontario, K1H 8, Canada
Pfizer Investigational Site
Toronto Ontario, M4N 3, Canada
Pfizer Investigational Site
Greenfield Park Quebec, J4V 2, Canada
Pfizer Investigational Site
Montreal Quebec, H2L 4, Canada
Pfizer Investigational Site
Montreal Quebec, H2X 3, Canada
Pfizer Investigational Site
Montreal Quebec, H3T 1, Canada
Pfizer Investigational Site
Quebec City Quebec, G1R 2, Canada
Pfizer Investigational Site
Sherbrooke Quebec, J1H 5, Canada
Pfizer Investigational Site
Hamilton, Ontario , L8N 4, Canada
Pfizer Investigational Site
Brno , 656 5, Czech Republic
Pfizer Investigational Site
Prague 5 , 150 0, Czech Republic
Pfizer Investigational Site
Sremska Kamenica Novi Sad, 21204, Former Serbia and Montenegro
Pfizer Investigational Site
Bonn NRW, 53105, Germany
Pfizer Investigational Site
Essen NRW, 45122, Germany
Pfizer Investigational Site
Mainz RP, D-551, Germany
Pfizer Investigational Site
Heraklion Creete, , Greece
Pfizer Investigational Site
Patra , , Greece
Pfizer Investigational Site
Budapest , H-112, Hungary
Pfizer Investigational Site
Roma RM, 00144, Italy
Pfizer Investigational Site
Foggia , 71100, Italy
Pfizer Investigational Site
Milano , 20132, Italy
Pfizer Investigational Site
Daugavpils , , Latvia
Pfizer Investigational Site
Riga , 1002, Latvia
Pfizer Investigational Site
Riga , 1079, Latvia
Pfizer Investigational Site
Vilnius , 2021, Lithuania
Pfizer Investigational Site
Monterrey Nuevo Leon, 64000, Mexico
Pfizer Investigational Site
Leon Guanajuato , 37000, Mexico
Pfizer Investigational Site
Nijmegen GA, 6525, Netherlands
Pfizer Investigational Site
Amsterdam , 1105 , Netherlands
Pfizer Investigational Site
Enschede , 7511 , Netherlands
Pfizer Investigational Site
Bytom , 41-90, Poland
Pfizer Investigational Site
Lodz , 93-50, Poland
Pfizer Investigational Site
Lublin , 20-09, Poland
Pfizer Investigational Site
Olsztyn , 10-22, Poland
Pfizer Investigational Site
Opole , 45-06, Poland
Pfizer Investigational Site
Poznan , 61-87, Poland
Pfizer Investigational Site
Siedlce , 08-11, Poland
Pfizer Investigational Site
Warszawa , 00-90, Poland
Pfizer Investigational Site
Warszawa , 02-78, Poland
Pfizer Investigational Site
Barnaul , 65605, Russian Federation
Pfizer Investigational Site
Kemerovo , 65000, Russian Federation
Pfizer Investigational Site
Moscow , 11547, Russian Federation
Pfizer Investigational Site
Moscow , 12135, Russian Federation
Pfizer Investigational Site
Moscow , 12528, Russian Federation
Pfizer Investigational Site
Moscow , 14342, Russian Federation
Pfizer Investigational Site
Obninsk , 24903, Russian Federation
Pfizer Investigational Site
Saint Petersburg , 18866, Russian Federation
Pfizer Investigational Site
Saint Petersburg , 19435, Russian Federation
Pfizer Investigational Site
Saint Petersburg , 19775, Russian Federation
Pfizer Investigational Site
Saint Petersburg , , Russian Federation
Pfizer Investigational Site
St Petersburg , 19775, Russian Federation
Pfizer Investigational Site
Ufa , 45000, Russian Federation
Pfizer Investigational Site
Ufa , , Russian Federation
Pfizer Investigational Site
Belgrade , 11000, Serbia
Pfizer Investigational Site
Banska Bystrica , 974 0, Slovakia
Pfizer Investigational Site
Bratislava , 833 1, Slovakia
Pfizer Investigational Site
Martin , 03659, Slovakia
Pfizer Investigational Site
Zlina , 012 0, Slovakia
Pfizer Investigational Site
Port Elizabeth Eastern Cape, 6006, South Africa
Pfizer Investigational Site
Johannesburg Gauteng, 2197, South Africa
Pfizer Investigational Site
Cape Town , 7505, South Africa
Pfizer Investigational Site
Gauteng , , South Africa
Pfizer Investigational Site
Oviedo Asturias, 33006, Spain
Pfizer Investigational Site
Badalona Barcelona, 08916, Spain
Pfizer Investigational Site
Barcelona , 08025, Spain
Pfizer Investigational Site
Madrid , 28040, Spain
Pfizer Investigational Site
Göteborg , 41345, Sweden
Pfizer Investigational Site
Stockholm , 171 7, Sweden
Pfizer Investigational Site
Uppsala , 751 8, Sweden
Pfizer Investigational Site
Taipei ROC, 112, Taiwan
Pfizer Investigational Site
Taichung , , Taiwan
Pfizer Investigational Site
Taipei , 104, Taiwan
Pfizer Investigational Site
Taoyuan , 333, Taiwan
Pfizer Investigational Site
Istanbul , , Turkey
Pfizer Investigational Site
Izmir , 35100, Turkey
Pfizer Investigational Site
Dnietropetrovsk , , Ukraine
Pfizer Investigational Site
Donetsk , 83 09, Ukraine
Pfizer Investigational Site
Kharkov , 61 03, Ukraine
Pfizer Investigational Site
Kiev , 03 14, Ukraine
Pfizer Investigational Site
Lviv , 79031, Ukraine
Pfizer Investigational Site
Zaporozhye , 69103, Ukraine
Pfizer Investigational Site
Manchester Lancashire, M20 4, United Kingdom
Pfizer Investigational Site
Glasgow Strathclyde, G11 6, United Kingdom
Pfizer Investigational Site
Sutton Surrey, SM2 5, United Kingdom
Pfizer Investigational Site
Nottingham , NG5 1, United Kingdom
Pfizer Investigational Site
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How clear is this clinincal trial information?

Study is for people with:

Kidney Cancer

Phase:

Phase 3

Estimated Enrollment:

626

Study ID:

NCT00065468

Recruitment Status:

Completed

Sponsor:


Pfizer

How clear is this clinincal trial information?

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