Lung Cancer Clinical Trial

Clinical Trial Finder Lung Cancer Trials

A Neoadjuvant Study of Nivolumab Plus Ipilimumab or Nivolumab Plus Chemotherapy Versus Chemotherapy Alone in Early Stage Non-Small Cell Lung Cancer (NSCLC)

See Locations Near You

Summary

The purpose of this neoadjuvant study is to compare nivolumab plus chemotherapy and chemotherapy alone in terms of safety and effectiveness, and to describe nivolumab plus ipilimumab's safety and effectiveness in treating resectable NSCLC.

This study has multiple primary endpoints.

View Eligibility Criteria

Eligibility Criteria

Inclusion Criteria:

Early stage IB-IIIA, operable non-small cell lung cancer, confirmed in tissue
Lung function capacity capable of tolerating the proposed lung surgery
Eastern Cooperative Oncology Group (ECOG) Performance Status of 0-1
Available tissue of primary lung tumor

Exclusion Criteria:

Presence of locally advanced, inoperable or metastatic disease
Participants with active, known or suspected autoimmune disease
Prior treatment with any drug that targets T cell co-stimulations pathways (such as checkpoint inhibitors)

Other protocol defined inclusion/exclusion criteria apply

Study is for people with:

Lung Cancer

Phase:

Phase 3

Estimated Enrollment:

505

Study ID:

NCT02998528

Recruitment Status:

Active, not recruiting

Sponsor:

Bristol-Myers Squibb

Check Your Eligibility

Let’s see if you might be eligible for this study.

What is your age and gender ?

Submit

There are 134 Locations for this study

See Locations Near You

Local Institution - 0121
Glendale Arizona, 85308, United States
Local Institution - 0081
Los Angeles California, 90017, United States
Local Institution - 0025
Denver Colorado, 80218, United States
Local Institution - 0007
Plainville Connecticut, 06062, United States
Memorial Regional Hospital
Hollywood Florida, 33201, United States
Local Institution - 0136
Miami Florida, 33136, United States
Cancer Institute Of Florida
Orlando Florida, 32804, United States
Orlando Health, Inc.
Orlando Florida, 32806, United States
Indian River Medical Center
Vero Beach Florida, 32960, United States
Northwest Georgia Oncology Center, P.C.
Marietta Georgia, 30060, United States
Local Institution - 0015
Chicago Illinois, 60611, United States
Local Institution - 0002
Chicago Illinois, 60637, United States
Illinois Cancer Specialists
Niles Illinois, 60714, United States
Local Institution - 0171
Fort Wayne Indiana, 46804, United States
Local Institution - 0170
Lexington Kentucky, 40536, United States
Local Institution - 0186
Louisville Kentucky, 40202, United States
University Medical Center New Orleans
New Orleans Louisiana, 70112, United States
Local Institution - 0151
Baltimore Maryland, 21237, United States
Local Institution - 0001
Baltimore Maryland, 21287, United States
Local Institution - 0006
Boston Massachusetts, 02215, United States
Local Institution - 0008
Boston Massachusetts, 02215, United States
Southcoast Center For Cancer
Fairhaven Massachusetts, 02719, United States
Local Institution - 0012
Detroit Michigan, 48202, United States
Local Institution - 0090
Hattiesburg Mississippi, 39401, United States
St Vincent Frontier Cancer Center
Billings Montana, 59102, United States
Comprehensive Cancer Centers of Nevada
Las Vegas Nevada, 89128, United States
Local Institution - 0009
Hackensack New Jersey, 07601, United States
Valley Hospital Luckow Pavili
Westwood New Jersey, 07675, United States
Local Institution - 0027
Albany New York, 12208, United States
Local Institution - 0011
New York New York, 10016, United States
Local Institution - 0140
High Point North Carolina, 27262, United States
Christ Hospital
Cincinnati Ohio, 45219, United States
MetroHealth Medical Center
Cleveland Ohio, 44109, United States
Genesis Health Care System
Zanesville Ohio, 43701, United States
Kaiser Permanente
Portland Oregon, 97227, United States
Local Institution - 0139
Portland Oregon, 97239, United States
Local Institution - 0010
Philadelphia Pennsylvania, 19111, United States
Local Institution - 0018
Pittsburgh Pennsylvania, 15212, United States
Local Institution - 0013
Charleston South Carolina, 29414, United States
Local Institution - 0021
Charleston South Carolina, 29425, United States
Bon Secours-St Francis Hosp
Greenville South Carolina, 29607, United States
Local Institution - 0092
Nashville Tennessee, 37203, United States
Local Institution - 0005
Nashville Tennessee, 37232, United States
Local Institution - 0035
Austin Texas, 78745, United States
Texas Oncology
Bedford Texas, 76022, United States
Local Institution - 0153
Fort Bliss Texas, 79918, United States
Local Institution - 0106
Houston Texas, 77090, United States
Southwest Cancer Center
Lubbock Texas, 79415, United States
Texas Cancer Center - Sherman
Sherman Texas, 75090, United States
Local Institution - 0143
Tyler Texas, 75701, United States
Local Institution - 0026
Waco Texas, 76712, United States
Intermountain Medical Center
Murray Utah, 84107, United States
Southwest Regional Cancer Clinic
Saint George Utah, 84770, United States
Local Institution - 0003
Salt Lake City Utah, 84112, United States
Local Institution - 0135
Burlington Vermont, 05405, United States
Local Institution - 0125
Fairfax Virginia, 22031, United States
Local Institution - 0198
Fredericksburg Virginia, 22408, United States
Local Institution - 0022
Capital Federal Buenos Aires, 1426, Argentina
Local Institution - 0023
Ciudad Autonoma De Buenos Aire Buenos Aires, 1181, Argentina
Local Institution - 0077
Belo Horizonte Minas Gerais, 30130, Brazil
Local Institution - 0076
Ijui RIO Grande DO SUL, 98700, Brazil
Local Institution - 0073
Porto Alegre RIO Grande DO SUL, 90610, Brazil
Fundacao Pio Xii Hosp Cancer De Barretos
Barretos Sao Paulo, 14784, Brazil
Local Institution - 0079
Brasilia São Paulo, 70200, Brazil
Local Institution - 0075
Rio de Janeiro , 22793, Brazil
Local Institution - 0095
Gatineau Quebec, J8P 7, Canada
Local Institution - 0138
Montreal Quebec, H2X 0, Canada
Local Institution - 0017
Montreal Quebec, H4A 3, Canada
Centre integre universitaire de sante et de services sociaux de la Mauricie-et-du-Centre-du-Quebec
Trois-Rivieres Quebec, G8Z 3, Canada
Local Institution - 0016
Saskatoon Saskatchewan, S7N 4, Canada
Local Institution - 0161
Beijing Beijing, 10014, China
Local Institution
Beijing Beijing, 10073, China
Local Institution - 0156
Beijing Beijing, 10085, China
Local Institution - 0190
Guangzhou Guangdong, 51009, China
Local Institution - 0192
Changsha Hunan, 41000, China
Local Institution - 0175
Changsha Hunan, 41001, China
Local Institution - 0193
Changsha Hunan, 41001, China
Local Institution - 0179
Nanchang Jiangxi, 33000, China
Local Institution
Nanchang Jiangxi, 33000, China
Local Institution
Changchun Jilin, 13001, China
Local Institution - 0159
XiAn Shan1xi, 71006, China
Local Institution - 0180
Xian Shan3xi, 71003, China
Local Institution - 0160
Shanghai Shanghai, 20003, China
Local Institution - 0178
Chengdu Sichuan, 61004, China
Local Institution - 0163
Tianjin Tianjin, 30006, China
Local Institution - 0189
Hangzhou Zhejiang, 31000, China
Local Institution - 0183
Hangzhou Zhejiang, 31001, China
Local Institution - 0182
Hangzhou Zhejiang, 31002, China
Local Institution - 0165
Shanghai , 20003, China
Local Institution - 0059
Marseille Cedex 20 , 13915, France
Local Institution - 0112
Paris Cedex 5 , 75248, France
Local Institution - 0060
Paris , 75018, France
Local Institution - 0064
Pierre Benite , 69495, France
Local Institution - 0061
Rennes Cedex 9 , 35033, France
Local Institution - 0113
Strasbourg , 67100, France
Local Institution - 0058
Toulouse , 31059, France
Local Institution - 0062
Tours Cedex 09 , 37044, France
Local Institution - 0019
Athens , 11527, Greece
Local Institution - 0122
Thessaloniki , 57001, Greece
Local Institution
Budapest , 1125, Hungary
Local Institution
Szekesfehervar , 8000, Hungary
Local Institution - 0068
Bari , 70124, Italy
Local Institution - 0080
Genova , 16132, Italy
Local Institution - 0070
Perugia , 06129, Italy
Local Institution - 0066
Ravenna , 48121, Italy
Local Institution - 0067
Roma , 00149, Italy
Local Institution - 0131
Nagoya-shi Aichi, 46400, Japan
Local Institution - 0118
Kashiwa-shi Chiba, 27785, Japan
Local Institution - 0111
Kitakyushu-shi Fukuoka, 80785, Japan
Local Institution - 0110
Fukushima-shi Fukushima, 96012, Japan
Local Institution - 0109
Hiroshima-Shi Hiroshima, 73485, Japan
Local Institution - 0147
Sapporo-shi Hokkaido, 00308, Japan
Local Institution - 0133
Kobe-shi Hyogo, 65000, Japan
Local Institution - 0123
Yokohama-shi Kanagawa, 24185, Japan
Local Institution - 0148
Sendai-shi Miyagi, 98008, Japan
Local Institution - 0108
Osaka-sayama-shi Osaka, 58985, Japan
Local Institution - 0127
Osaka-shi Osaka, 54185, Japan
Local Institution - 0119
Sakai-shi Osaka, 59185, Japan
Local Institution - 0132
Sunto-gun Shizuoka, 41187, Japan
Local Institution - 0126
Bunkyo-ku Tokyo, 11384, Japan
Local Institution - 0120
Shinjuku-ku Tokyo, 16000, Japan
Local Institution - 0124
Tokyo , 11386, Japan
Local Institution - 0097
Busan , 49267, Korea, Republic of
Local Institution - 0098
Hwasun , 58128, Korea, Republic of
Local Institution - 0105
Seoul , 08308, Korea, Republic of
Local Institution - 0050
Craiova , 20034, Romania
Local Institution - 0051
Romania , 40001, Romania
Local Institution - 0069
Sector 2 , 02232, Romania
Local Institution - 0028
Barcelona , 08035, Spain
Local Institution - 0029
Madrid , 28041, Spain
Local Institution - 0031
Majadahonda - Madrid , 28222, Spain
Local Institution - 0102
New Taipei City , 235, Taiwan
Local Institution - 0107
Taichung , 40721, Taiwan
Local Institution - 0099
Taipei , 11031, Taiwan
Local Institution - 0100
Taipei , 11217, Taiwan
Local Institution - 0093
Adana , 01060, Turkey
Local Institution - 0084
Ankara , 06100, Turkey
Local Institution - 0115
Istanbul , 34098, Turkey
Load More

How clear is this clinincal trial information?

Study is for people with:

Lung Cancer

Phase:

Phase 3

Estimated Enrollment:

505

Study ID:

NCT02998528

Recruitment Status:

Active, not recruiting

Sponsor:


Bristol-Myers Squibb

How clear is this clinincal trial information?

Clinical Trial Resources

Why I’d Choose a Clinical Trial For Myself
Clinical Trials Can be Life-Saving for Some
When Should I Consider Clinical Trials?
×

Introducing, the Journey Bar

Use this bar to access information about the steps in your cancer journey.

Please confirm you are a US based health care provider:

Yes, I am a health care Provider No, I am not a health care provider