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A Pilot Study to Develop Predictive Biomarkers for the Response to Immunotherapy in Lung Cancer Summary Several immune checkpoint inhibitors targeting the PD-1 pathway have been developed with clinical trials showing an approximately 20% durable response in unselected patients with advanced non-small cell lung cancer (NSCLC). At the moment, no clear biomarker exists to accurately predict anti-PD1/PDL1 tumor responsiveness. The goal of this study is to broadly discover and evaluate the utility of blood based biomarkers for use in measuring and predicting response to immunotherapy in patients with lung cancer.
View Eligibility Criteria Eligibility Criteria Inclusion Criteria: Advanced Metastatic NSCLC Scheduled to initiate an immune checkpoint inhibitor Age >= 18 years Able to provide informed consent Exclusion Criteria: Other, unrelated, concomitant active, invasive malignancy
Check Your Eligibility
Let’s see if you might be eligible for this study.
What is your age and gender ?
There is 1 Location for this study
Abramson Cancer Center of the University of Pennsylvania Philadelphia Pennsylvania, 19104, United States
How clear is this clinincal trial information?
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