Lung Cancer Clinical Trial

A Pilot Study to Develop Predictive Biomarkers for the Response to Immunotherapy in Lung Cancer

Summary

Several immune checkpoint inhibitors targeting the PD-1 pathway have been developed with clinical trials showing an approximately 20% durable response in unselected patients with advanced non-small cell lung cancer (NSCLC). At the moment, no clear biomarker exists to accurately predict anti-PD1/PDL1 tumor responsiveness. The goal of this study is to broadly discover and evaluate the utility of blood based biomarkers for use in measuring and predicting response to immunotherapy in patients with lung cancer.

View Eligibility Criteria

Eligibility Criteria

Inclusion Criteria:

Advanced Metastatic NSCLC
Scheduled to initiate an immune checkpoint inhibitor
Age >= 18 years
Able to provide informed consent

Exclusion Criteria:

Other, unrelated, concomitant active, invasive malignancy

Study is for people with:

Lung Cancer

Estimated Enrollment:

88

Study ID:

NCT03047616

Recruitment Status:

Completed

Sponsor:

Abramson Cancer Center of the University of Pennsylvania

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There is 1 Location for this study

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Abramson Cancer Center of the University of Pennsylvania
Philadelphia Pennsylvania, 19104, United States

How clear is this clinincal trial information?

Study is for people with:

Lung Cancer

Estimated Enrollment:

88

Study ID:

NCT03047616

Recruitment Status:

Completed

Sponsor:


Abramson Cancer Center of the University of Pennsylvania

How clear is this clinincal trial information?

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