Lung Cancer Clinical Trial

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A Randomized Phase 3 Trial of Pemetrexed and Cisplatin Versus Gemcitabine and Cisplatin in Patients With Locally Advanced or Metastatic Non Small Cell Lung Cancer

Summary

This study is a randomized Phase 3 study comparing pemetrexed and cisplatin combination to gemcitabine and cisplatin for the treatment of Non Small Cell Lung Cancer (NCSLC). Gemcitabine plus cisplatin is currently the standard of care for NSCLC. It is thought that pemetrexed plus cisplatin may be as effective and may have fewer side effects than the standard of care.

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Eligibility Criteria

Inclusion Criteria:

Diagnosis of NSCLC Stage IIIB not amenable to curative treatment or Stage IV.
No prior chemotherapy for lung cancer.
Patients must have at least one uni-dimensionally measurable lesion.
Prior radiation therapy to less than 25% of bone marrow, whole pelvis not allowed. Radiation must be completed at least 4 weeks prior to study enrollment.

Exclusion Criteria:

Treatment with any drug within the last 30 days that has not received regulatory approval.
Serious cardiac condition.
Serious medical disorder in addition to NSCLC that would make it difficult for the patient to complete the study.
Inability or unwillingness to take folic acid or Vitamin B12 supplementation.
Presence of fluid retention that cannot be controlled by drainage.

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There is 1 Location for this study

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For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Monday-Friday from 9:00 AM to 5:00 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician
Sacramento California, , United States

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Clinical Trial Finder Lung Cancer Trials

A Randomized Phase 3 Trial of Pemetrexed and Cisplatin Versus Gemcitabine and Cisplatin in Patients With Locally Advanced or Metastatic Non Small Cell Lung Cancer

Summary

Eligibility Criteria

Study is for people with:

Phase:

Estimated Enrollment:

Study ID:

Recruitment Status:

Sponsor:

Check Your Eligibility

There is 1 Location for this study

Study is for people with:

Phase:

Estimated Enrollment:

Study ID:

Recruitment Status:

Sponsor:

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Multiple Myeloma

Discover local Multiple Myeloma resources:

Ovarian Cancer

Discover local Ovarian Cancer resources:

Multiple Myeloma: Main Page

Discover local Multiple Myeloma resources:

Discover Local Multiple Myeloma resources:

Ovarian Cancer: Main Page

Discover local Ovarian Cancer resources:

Discover Local Ovarian Cancer resources:

Clinical Trial Finder Lung Cancer Trials

A Randomized Phase 3 Trial of Pemetrexed and Cisplatin Versus Gemcitabine and Cisplatin in Patients With Locally Advanced or Metastatic Non Small Cell Lung Cancer

Summary

Eligibility Criteria

Study is for people with:

Phase:

Estimated Enrollment:

Study ID:

Recruitment Status:

Sponsor:

Check Your Eligibility

There is 1 Location for this study

Study is for people with:

Phase:

Estimated Enrollment:

Study ID:

Recruitment Status:

Sponsor:

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