Lung Cancer Clinical Trial

A Study of Amivantamab and Lazertinib Combination Therapy Versus Osimertinib in Locally Advanced or Metastatic Non-Small Cell Lung Cancer

Summary

The purpose of this study is to assess the efficacy of the amivantamab and lazertinib combination, compared with osimertinib, in participants with epidermal growth factor receptor (EGFR) mutation (Exon 19 deletions [Exon 19del] or Exon 21 L858R substitution) positive, locally advanced or metastatic non-small cell lung cancer (NSCLC).

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Full Description

Worldwide, lung cancer is the most commonly diagnosed cancer. In NSCLC the most prevalent actionable driver mutations result in the activation of epidermal growth factor receptor (EGFR). Osimertinib and Lazertinib are EGFR tyrosine kinase inhibitors (TKIs). Amivantamab is a novel bispecific antibody that targets the extracellular domain of both EGFR and MET and can inhibit tumor growth driven by EGFR and mesenchymal-epithelial transition (MET) receptors. Lazertinib inhibits primary activating Exon 19dell and Exon 21 L858R substitution EGFR mutations, and the EGFR T790M+ resistance mutation. The hypothesis is that the amivantamab and lazertinib combination (Arm A) will demonstrate superior PFS compared with single-agent osimertinib (Arm B). The study consists of 3 phases: Screening Phase, Treatment Phase and Follow-up Phase. Participants will undergo response evaluation criteria in solid tumors (RECIST 1.1), pharmacokinetics, and safety evaluations (adverse events, laboratory tests, vital sign measurements, physical examinations).

View Eligibility Criteria

Eligibility Criteria

Inclusion Criteria:

Participant must have newly diagnosed histologically or cytologically confirmed, locally advanced or metastatic non-small cell lung cancer (NSCLC) that is treatment naive and not amenable to curative therapy including surgical resection or chemoradiation
The tumor harbors exon 19 deletions (Exon 19del) or Exon 21 L858R substitution, as detected by an food and drug administration (FDA)-approved or other validated test in a clinical laboratory improvement amendments (CLIA) certified laboratory (sites in the United states [US]) or an accredited local laboratory (sites outside of the US) in accordance with site standard of care
Mandatory submission of unstained tissue from tumor (in a quantity sufficient to allow for central analysis of EGFR mutation status and blood (for circulating tumor deoxyribonucleic acid [ctDNA], digital droplet polymerase chain reaction [ddPCR], and pharmacogenomic analysis)
Any toxicities from prior anticancer therapy must have resolved to common terminology criteria for adverse events (CTCAE) Grade 1 or baseline level
Participant must have at least 1 measurable lesion, according to response evaluation criteria in solid tumors (RECIST) v1.1 that has not been previously irradiated. Measurable lesions should not have been biopsied during screening, but if only 1 non-irradiated measurable lesion exists, it may undergo a diagnostic biopsy and be acceptable as a target lesion, provided the baseline tumor assessment scans are performed at least 14 days after the biopsy

Exclusion Criteria:

Participant has received any prior systemic treatment at any time for locally advanced Stage III or metastatic Stage IV disease (adjuvant or neoadjuvant therapy for Stage I or II disease is allowed, if administered more than 12 months prior to the development of locally advanced or metastatic disease)
Participant has an active or past medical history of leptomeningeal disease
Participant with untreated spinal cord compression. A participant that has been definitively treated with surgery or radiation and has a stable neurological status for at least 2 weeks prior to randomization is eligible provided they are off corticosteroid treatment or receiving low-dose corticosteroid treatment less than or equal to (<=) 10 milligrams per day (mg/day) prednisone or equivalent
Participant has an active or past medical history of interstitial lung disease (ILD)/pneumonitis, including drug-induced or radiation ILD/pneumonitis
Participant has known allergy, hypersensitivity, or intolerance to the excipients used in formulation of amivantamab, lazertinib, or osimertinib, or any contraindication to the use of osimertinib
Participant has symptomatic brain metastases. A participant with asymptomatic or previously treated and stable brain metastases may participate in this study

Study is for people with:

Lung Cancer

Phase:

Phase 3

Estimated Enrollment:

1074

Study ID:

NCT04487080

Recruitment Status:

Active, not recruiting

Sponsor:

Janssen Research & Development, LLC

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There are 262 Locations for this study

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Arizona Oncology Associates, PC - HAL
Goodyear Arizona, 85395, United States
Yuma Regional Medical Center
Yuma Arizona, 85364, United States
City of Hope Long Beach Elm
Long Beach California, 90813, United States
University of California, Irvine
Orange California, 92868, United States
Rocky Mountain Cancer Centers
Lone Tree Colorado, 80124, United States
Cancer Specialists of North Florida
Jacksonville Florida, 32256, United States
University Cancer & Blood Center, LLC
Athens Georgia, 30607, United States
East Jefferson General Hospital
Metairie Louisiana, 70006, United States
Maryland Oncology Hematology, PA
Columbia Maryland, 21044, United States
Henry Ford Hospital
Detroit Michigan, 48202, United States
Minnesota Oncology Hematology, P.A.
Edina Minnesota, 55435, United States
Mayo Clinic
Rochester Minnesota, 55905, United States
Washington University School of Medicine
Saint Louis Missouri, 63110, United States
Astera Cancer Care
East Brunswick New Jersey, 08816, United States
Willamette Valley Cancer Institute and Research Center
Eugene Oregon, 97401, United States
University of Pittsburgh Medical Center
Pittsburgh Pennsylvania, 15232, United States
Sarah Cannon Research Institute
Nashville Tennessee, 37203, United States
Texas Oncology P.A.
Austin Texas, 78745, United States
Oncology Consultants - Texas
Houston Texas, 77030, United States
Virginia Cancer Specialists
Fairfax Virginia, 22031, United States
Instituto Alexander Fleming
Buenos Aires , C1428, Argentina
Centro Oncológico Korben
Ciudad Autónoma de Buenos Aires , C1426, Argentina
Hospital Privado Centro Medico de Cordoba
Cordoba , X5016, Argentina
Centro Oncologico Riojano Integral (Cori)
La Rioja , F5300, Argentina
Clínica Viedma
Viedma , R8500, Argentina
Flinders Medical Centre
Bedford Park , 5042, Australia
Austin Hospital
Heidelberg , 3084, Australia
Cabrini Medical Centre
Malvern , 3144, Australia
St John of God Hospital Murdoch
Murdoch , 6150, Australia
Sir Charles Gairdner Hospital
Nedlands , 6009, Australia
Westmead Hospital
Westmead , 2145, Australia
Southern Medical Day Care Centre
Wollongong , 2500, Australia
Princess Alexandra Hospital
Woolloongabba , 4102, Australia
Cliniques Universitaires Saint-Luc
Brussel , 1200, Belgium
Grand Hôpital de Charleroi, site Notre Dame
Charleroi , 6000, Belgium
UZ Leuven
Leuven , 3000, Belgium
Clinique Saint Pierre
Ottignies , 1340, Belgium
Algemeen Ziekenhuis Delta
Roeselare , 8800, Belgium
Fundacao Pio Xii - Hospital De Cancer De Barretos
Barretos , 14784, Brazil
Cetus Oncologia
Belo Horizonte , 30110, Brazil
Hospital Evangélico de Cachoeiro de Itapemirim
Cachoeiro de Itapemirim , 29308, Brazil
Ynova Pesquisa Clinica
Florianopolis , 88020, Brazil
Oncosite - Centro de Pesquisa Clínica em Oncologia Ltda
Ijui , 98700, Brazil
Liga Norte Riograndense Contra O Cancer
Natal , 59062, Brazil
UPCO Unidade de Pesquisa Clinica em Oncologia
Pelotas , 96020, Brazil
Irmandade Santa Casa de Misericordia de Porto Alegre
Porto Alegre , 90020, Brazil
Centro de Pesquisa em Oncologia - PUCRS
Porto Alegre , 90610, Brazil
Ministerio da Saude - Instituto Nacional do Cancer
Rio De Janeiro , 20231, Brazil
Oncoclínicas
Rio de Janeiro , 22250, Brazil
Instituto D'Or de Pesquisa e Ensino (IDOR)
Rio de Janeiro , 22281, Brazil
Fundação Faculdade de Medicina - Instituto do Cancer do Estado de São Paulo
Sao Paulo , 01246, Brazil
Fundação Antônio Prudente - A.C. Camargo Cancer Center
Sao Paulo , 01509, Brazil
Núcleo de Pesquisa São Camilo
Sao Paulo , 04014, Brazil
IOS - Instituto de Oncologia de Sorocaba Dr. Gilson Delgado
Sorocaba , 18030, Brazil
William Osler Health System
Brampton Ontario, L6R 3, Canada
Juravinski Cancer Centre
Hamilton Ontario, L8V 5, Canada
The Ottawa Hospital Cancer Centre
Ottawa Ontario, K1H 8, Canada
McGill University Health Centre
Montreal Quebec, H4A 3, Canada
Beijing Friendship Hospital, Capital Medical University
Beijing , 10005, China
Beijing Cancer Hospital
Beijing , 10014, China
Chinese PLA General Hospital
Beijing , 10085, China
Beijing Chest hospital, Capital medical university
Beijing , 10119, China
Jilin cancer hospital
Changchun , 13000, China
Hunan Cancer hospital
Changsha , 41001, China
The First People's Hospital Of Changzhou
Changzhou , 21300, China
Sichuan Cancer Hospital
Chengdu , 61004, China
West China Hospital, Sichuan University
Chengdu , 61004, China
Southwest Hospital
ChongQing , 40003, China
The First Affiliated Hospital, Sun Yat-sen University
Guang Zhou , 51008, China
Sun Yat-Sen Memorial Hospital Sun Yat-sen University
Guangzhou , 51012, China
Zhejiang Cancer Hospital
Hang Zhou , 31002, China
Second Affiliated Hospital, School of Medicine, Zhejiang University
Hangzhou , 31000, China
The Second Affiliated Hospital of Zhejiang University College of Medicine
Hangzhou , 31000, China
Sir Run Run Shaw Hospital, Zhejiang University School of Medicine
Hangzhou , 31001, China
Harbin medical university cancer hospital
Harbin , 15008, China
Huizhou Municipal Central Hospital
Huizhou , 51600, China
Taizhou Hospital of Zhejiang Province
Linhai , 31700, China
Nantong Tumor Hospital
Nantong , 22630, China
Ruijin Hospital, Shanghai Jiao Tong University
Shanghai , 20002, China
Shanghai Chest Hospital
Shanghai , 20003, China
Fudan University Shanghai Cancer Center
Shanghai , 20003, China
Shanghai East Hospital
Shanghai , 20012, China
Shengjing Hospital of China Medical University
Shenyang , 11002, China
Tianjin Medical University General Hospital
Tianjin , 30005, China
Cancer Hospital of Xinjiang Medical University
Urumchi , 83000, China
The First Affiliated Hospital of Wenzhou Medical University
Wenzhou , 32500, China
TongJi Hospital of TongJi Medical College of Huazhong University of Science & Technology
Wuhan , 43003, China
The First Affiliated Hospital of Xi'an Jiaotong University
Xi'an , 71006, China
Yantai Yuhuangding Hospital
Yantai , 26400, China
Henan Cancer Hospital
Zhengzhou , 45000, China
Institut Bergonié
Bordeaux , 33000, France
Hospices Civils de Lyon HCL
Bron , 69500, France
CHU de Grenoble - Hôpital Albert Michallon
La Tronche , 38700, France
Institute Coeur Poumon
Lille , 59000, France
CHU de Limoges
Limoges , 87000, France
Hopital Nord
Marseille Cedex 20 , 13915, France
Institut Curie
Paris , 75005, France
Hôpital Tenon
Paris , 75970, France
CHU Bordeaux
Pessac , 33604, France
CHU Nantes
Sain-Herblain , 44800, France
HIA Begin
Saint Mande , 94163, France
CHU Bretonneau
Tours , 37000, France
Institut Gustave Roussy
Villejuif Cedex , 94805, France
Zentralklinik Bad Berka GmbH
Bad Berka , 99437, Germany
Helios Klinikum Emil von Behring GmbH
Berlin , 14165, Germany
Universitaetsklinikum Essen
Essen , 45147, Germany
Asklepios Klinik Gauting GmbH - Asklepios Fachkliniken München-Gauting
Gauting , 82131, Germany
Städtisches Krankenhaus Martha-Maria Halle-Dölau gGmbH
Halle (Saale) , 06120, Germany
Thoraxklinik am Universitätsklinikum Heidelberg
Heidelberg , 69126, Germany
Onkologische Schwerpunktpraxis
Heilbronn , 74072, Germany
Kliniken der Stadt Koeln gGmbH
Koeln , 51109, Germany
POIS Leipzig GbR
Leipzig , 04357, Germany
Pius-Hospital Oldenburg
Oldenburg , 26121, Germany
Robert-Bosch-Krankenhaus - Klinik Schillerhoehe
Stuttgart , 70376, Germany
Orszagos Koranyi Tbc es Pulmonologiai Intezet
Budapest , H-152, Hungary
Veszprém Megyei Tudőgyógyintézet
Farkasgyepü , 8582, Hungary
Mátrai Gyógyintézet-Bronchológia
Gyöngyös , 3233, Hungary
Fejer Megyei Szent Gyorgy Egyetemi Oktatokorhaz
Szekesfehervar , 8000, Hungary
Markusovszky Egyetemi Oktatokorhaz
Szombathely , 9700, Hungary
Tudogyogyintezet Torokbalint
Torokbalint , 2045, Hungary
Basavatarakam Indo-American Hospital
Hyderabad , 50003, India
Tata Medical Center
Kolkata , 70016, India
Tata Memorial Hospital
Mumbai , 40001, India
HCG Manavta Cancer Centre
Nasik , 42200, India
Noble Hospital Pvt Ltd
Pune , 41101, India
Rambam Health Corporation
Haifa , 31096, Israel
Hadassah Medical Center
Jerusalem , 91120, Israel
Meir Medical Center
Kfar Saba , 44281, Israel
Rabin Medical Center
Petah Tikva , 49100, Israel
Chaim Sheba Medical Center
Ramat Gan , 52621, Israel
Tel-Aviv Sourasky Medical Center
Tel-Aviv , 64239, Israel
Ospedale San Giuseppe Moscati di Avellino
Avellino , 83100, Italy
Azienda Ospedaliero Univ. Policlinico Gaspare Rodolico
Catania , 95123, Italy
Istituto Scientifico Romagnolo per lo Studio e la Cura dei Tumori
Meldola , 47014, Italy
Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico
Milano , 20122, Italy
IRCCS Ospedale San Raffaele
Milano , 20132, Italy
Fondazione IRCCS Istituto Nazionale dei Tumori
Milano , 20133, Italy
Istituto Europeo di Oncologia
Milano , 20141, Italy
San Gerardo Hospital
Monza , 20052, Italy
Ospedale Monaldi
Napoli , 80100, Italy
Aou San Luigi Gonzaga
Orbassano , 10043, Italy
Ospedale S. Maria Delle Croci
Ravenna , 48121, Italy
Irccs Gemelli
Roma , 00168, Italy
Istituto Clinico Humanitas
Rozzano , 20089, Italy
Juntendo University Hospital
Bunkyo-Ku , 113-8, Japan
National Cancer Center Hospital
Chuo-Ku , 104-0, Japan
National Hospital Organization Kyushu Medical Center
Fukuoka , 810-8, Japan
National Hospital Organization Himeji Medical Center
Himeji , 670-8, Japan
Kansai Medical University Hospital
Hirakata , 573-1, Japan
Kanazawa University Hospital
Kanazawa , 920-8, Japan
National Cancer Center Hospital East
Kashiwa , 277-8, Japan
Kurume University Hospital
Kurume , 830-0, Japan
Matsusaka Municipal Hospital
Matsusaka , 515-8, Japan
Niigata Cancer Center Hospital
Niigata , 951-8, Japan
Okayama University Hospital
Okayama , 700-8, Japan
Kindai University Hospital
Osaka-Sayama-shi , 589-8, Japan
National Hospital Organization Shibukawa Medical Center
Shibukawa , 377-0, Japan
The Cancer Institute Hospital of JFCR
Tokyo , 135-8, Japan
National Hospital Organization Tokyo Medical Center
Tokyo , 152-8, Japan
Ehime University Hospital
Toon-shi , 791-0, Japan
National Hospital Organization Osaka Toneyama Medical Center
Toyonaka-shi , 560-8, Japan
Wakayama Medical University Hospital
Wakayama , 641-8, Japan
National Hospital Organization Iwakuni Clinical Center
Yamaguchi , 740-8, Japan
National Hospital Organization Yamaguchi Ube Medical Center
Yamaguchi , 755-0, Japan
Inje University Haeundae Paik Hospital
Busan , 48108, Korea, Republic of
Chungbuk National University Hospital
Cheongju-si , 28644, Korea, Republic of
Seoul National University Bundang Hospital
Gyeonggi-do , 13620, Korea, Republic of
Kangbuk Samsung Hospital
Seoul , 03181, Korea, Republic of
Severance Hospital, Yonsei University Health System
Seoul , 03722, Korea, Republic of
Asan Medical Center
Seoul , 05505, Korea, Republic of
Samsung Medical Center
Seoul , 06351, Korea, Republic of
The Catholic University of Korea, Seoul St. Mary's Hospital
Seoul , 06591, Korea, Republic of
Korea University Guro Hospital
Seoul , 8308, Korea, Republic of
Hospital Pulau Pinang
George Town , 10990, Malaysia
Hospital Sultan Ismail
Johor Bahru , 81100, Malaysia
Hospital Kuala Lumpur
Kuala Lumpur , 50586, Malaysia
University Malaya Medical Centre
Kuala Lumpur , 59100, Malaysia
Hospital Tengku Ampuan Afzan
Kuantan , 25100, Malaysia
Beacon Hospital Sdn. Bhd.
Petaling Jaya , 46050, Malaysia
Mexico Centre for Clinical Research, S.A. de C.V.
Ciudad de Mexico , 03100, Mexico
Médica Sur
Ciudad de Mexico , 14050, Mexico
Hospital Civil de Guadalajara Fray Antonio Alcalde
Guadalajara , 44280, Mexico
CIMOVA, Morals Vargas Centro de Investigación SC
Leon , 37000, Mexico
Health Pharma Professional Research
Mexico , 03100, Mexico
Instituto Nacional de Cancerologia
Mexico , 14080, Mexico
i Can Oncology Center
Monterrey , 64710, Mexico
Oncologia Integral Satelite
Naucalpan , 53100, Mexico
Rijnstate Ziekenhuis
Arnhem , 6815 , Netherlands
Ziekenhuis St Jansdal
Harderwijk , 3844 , Netherlands
UMC Radboud
Nijmegen , 6525A, Netherlands
Jeroen Bosch Ziekenhuis
s-Hertogenbosch , 5223 , Netherlands
Centrum Onkologii im. Prof. F. Lukaszczyka
Bydgoszcz , 85-79, Poland
Uniwersyteckie Centrum Kliniczne
Gdańsk , 80-21, Poland
Szpitale Pomorskie Sp. z o.o.
Gdynia , 81-51, Poland
Warminsko-Mazurskie Centrum Chorob Pluc w Olsztynie
Olsztyn , 10-35, Poland
Private Specialist Hospitals - MedPolonia
Poznan , 60-69, Poland
Narodowy Instytut Onkologii im. Marii Sklodowskiej-Curie - Panstwowy Instytut Badawczy
Warszawa , 02-78, Poland
Centro Hospitalar Lisboa Norte EPE - Hospital Pulido Valente
Lisboa , 1769-, Portugal
Centro Hospitalar Universitario do Porto, EPE
Porto , 4099-, Portugal
Hospital CUF Porto
Porto , 4100-, Portugal
Instituto Portugues de Oncologia
Porto , 4200-, Portugal
Pan American Center for Oncology Trials LLC
Rio Piedras , 00935, Puerto Rico
Irkutsk Regional Oncology Dispensary
Irkutsk , 66403, Russian Federation
Moscow City Oncology Hospital № 62
Krasnogorsk , 14342, Russian Federation
Krasnoyarsk Regional Oncology Dispensary
Krasnoyarsk , 66013, Russian Federation
Leningrad Regional Oncology Dispensary
Kuzmolovsky , 18866, Russian Federation
MCK
Moscow , 11553, Russian Federation
City Clinical Hospital #1
Nalchik , 36000, Russian Federation
Nizhny Novgorod Regional Oncological Dispensary
Nizhniy Novgorod , 60300, Russian Federation
Omsk Clinical Oncology Dispensary
Omsk , 66401, Russian Federation
Current medical technologies
Saint Petersburg , 19012, Russian Federation
N.N. Petrov Research Institute Of Oncology
Saint Petersburg , 19775, Russian Federation
Oncology Medical Clinics AV Medical group
St-Petersburg , 19600, Russian Federation
Tambov Regional Oncology Clinical Dispansary
Tambov , 39201, Russian Federation
Tomsk Cancer Research Institute
Tomsk , 63405, Russian Federation
Bashkir State Medical University
Ufa , 45008, Russian Federation
Yaroslavl Regional Clinical Oncology Hospital
Yaroslavl , 15005, Russian Federation
Hosp. Univ. A Coruña
A Coruña , 15006, Spain
Inst. Cat. D'Oncologia-Badalona
Badalona , 08916, Spain
Hosp. de La Santa Creu I Sant Pau
Barcelona , 08025, Spain
Hosp. Univ. Quiron Dexeus
Barcelona , 08028, Spain
Hosp. Univ. Vall D Hebron
Barcelona , 08035, Spain
Hosp. Univ. de Burgos
Burgos , 09006, Spain
Institut Català D'Oncologia Girona
Girona , 17007, Spain
Hosp. Gral. Univ. Gregorio Marañon
Madrid , 28007, Spain
Hosp. Univ. 12 de Octubre
Madrid , 28041, Spain
Hosp. Univ. La Paz
Madrid , 28046, Spain
Hosp. Univ. Pta. de Hierro Majadahonda
Majadahonda , 28222, Spain
Hosp. Regional Univ. de Malaga
Málaga , 29010, Spain
Clinica Univ. de Navarra
Pamplona , 31008, Spain
Hosp. Virgen Del Rocio
Seville , 41013, Spain
Hosp. Gral. Univ. Valencia
Valencia , 46014, Spain
Hosp. Clinico Univ. Lozano Blesa
Zaragoza , 50009, Spain
Kaohsiung Medical University Chung-Ho Memorial Hospital
Kaohsiung , 807, Taiwan
E-DA Hospital
Kaohsiung , 824, Taiwan
Chang Gung Medical Foundation
Kaohsiung , 833, Taiwan
Taipei Medical University Shuang Ho Hospital
New Taipei , 23561, Taiwan
Chung Shan Medical University Hospital
Taichung , 402, Taiwan
China Medical University Hospital
Taichung , 40447, Taiwan
National Cheng Kung University Hospital
Tainan , 704, Taiwan
National Taiwan University Hospital
Taipei City , 10002, Taiwan
Phramongkutklao Hospital and Medical College
Bangkok , 10400, Thailand
Siriraj Hospital
Bangkok , 10700, Thailand
Chiang Mai University
Chiangmai , 50200, Thailand
Songklanagarind Hospital, Prince of Songkla University
Songkla , 90110, Thailand
Adana City Hospital
Adana , 01060, Turkey
Başkent University Medical Faculty Adana Application and Research Center
Adana , 01250, Turkey
Gazi University Hospital
Ankara , 6560, Turkey
Ankara Bilkent City Hospital
Ankara , 6800, Turkey
Trakya University Medical Faculty
Edirne , 22030, Turkey
Istanbul Universitesi Cerrahpasa Tip Fakultesi Ic Hastaliklari Anabilim Dali Medikal Onkoloji Bd
Istanbul , 34098, Turkey
Medipol Mega University Hospital
Istanbul , 34214, Turkey
T.C. Saglik Bakanlıgi Goztepe Prof. Dr. Suleyman Yalcın Sehir Hastanesi
Istanbul , 34722, Turkey
Izmir Ekonomi Universitesi Medical Park Hastanesi
Izmir , 35580, Turkey
Necmettin Erbakan University Meram Medical Faculty
Konya , 42080, Turkey
Dnipropetrovsk State Medical Academy, Dnipropetrovsk City Multifield Clinical Hospital # 4
Dnipro , 49102, Ukraine
Municipal non-profit enterprise 'Regional Center of Oncology'
Kharkiv , 61070, Ukraine
Medical Center 'Ok Clinic' of LLC 'International Institute of Clinical Studies'
Kyiv , 02091, Ukraine
National Cancer Institute
Kyiv , 03022, Ukraine
Municipal Oncology Centre of Uzhgorod Central Municipal Clinical Hospitlal
Uzhgorod , 88000, Ukraine
Edinburgh Cancer Centre Western General
Edinburgh , EH4 2, United Kingdom
UCL Cancer Institute
London , NW1 2, United Kingdom
Chelsea And Westminster Hospital
London , SW10 , United Kingdom
The Royal Marsden NHS Trust
London , SW3 6, United Kingdom
Christie NHS Foundation Trust
Manchester , M20 4, United Kingdom
Nottingham University Hospitals NHS Trust
Nottingham , NG5 1, United Kingdom
The Royal Marsden NHS Trust
Sutton , SM2 5, United Kingdom

How clear is this clinincal trial information?

Study is for people with:

Lung Cancer

Phase:

Phase 3

Estimated Enrollment:

1074

Study ID:

NCT04487080

Recruitment Status:

Active, not recruiting

Sponsor:


Janssen Research & Development, LLC

How clear is this clinincal trial information?

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