Lung Cancer Clinical Trial

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A Study of BMS-833923 With Carboplatin and Etoposide Followed by BMS-833923 Alone in Subjects With Extensive-Stage Small Cell Lung Cancer

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Summary

The purpose of this study is to determine the maximum tolerated dose (MTD) of BMS-833923 administered in combination with carboplatin and etoposide followed by BMS-833923 alone in subjects with extensive-stage Small Cell Lung Cancer (SCLC).

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Eligibility Criteria

Inclusion Criteria:

Histologically or cytologically confirmed small cell lung cancer, without prior chemotherapy treatment
Men and Women at least 18 years old
Eastern Cooperative Oncology Group (ECOG) status 0-2

Exclusion Criteria:

Significant cardiovascular disease
Prior treatment of small cell lung cancer is not permitted, except for palliative radiation to a limited field excluding the chest (e.g. for painful metastasis).
Symptomatic brain metastases
Women pregnant or breastfeeding
Women of childbearing potential (WOCBP) unwilling/unable to use acceptable method to avoid pregnancy
Uncontrolled medical disorder or active infection
Concurrent therapy with any other investigational product

Study is for people with:

Lung Cancer

Phase:

Phase 1

Estimated Enrollment:

5

Study ID:

NCT00927875

Recruitment Status:

Completed

Sponsor:

Bristol-Myers Squibb

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There are 5 Locations for this study

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Karmanos Cancer Institute
Detroit Michigan, 48201, United States
Local Institution
East Bentleigh Victoria, 3165, Australia
Local Institution
Edmonton Alberta, T6G 1, Canada
Local Institution
Ottawa Ontario, K1H 8, Canada
Local Institution
Villejuif Cedex , 94800, France
Local Institution
Dublin , , Ireland
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How clear is this clinincal trial information?

Study is for people with:

Lung Cancer

Phase:

Phase 1

Estimated Enrollment:

5

Study ID:

NCT00927875

Recruitment Status:

Completed

Sponsor:


Bristol-Myers Squibb

How clear is this clinincal trial information?

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