Lung Cancer Clinical Trial
A Study of Stereotactic Radiosurgery (SRS) for People With Lung Cancer That Has Spread to the Brain
Histologic diagnosis of small cell lung cancer
Radiographic diagnosis of up to 10 brain metastases on contrast-enhanced MRI
Age 18 and above
Performance status KPS 60-100/ECOG 0-2
Female patients must be of non-reproductive potential or have a negative serum pregnancy test at the time of enrollment
The patient or legally authorized representative is able to provide informed consent
Unable to undergo contrast-enhanced MRI brain or spine
Leptomeningeal disease confirmed on lumbar puncture, MRI brain, or MRI spine
Pregnant or lactating women
Prior brain-directed radiotherapy
Uncontrolled systemic disease without reasonable systemic therapy options felt likely to result in death as observed on CT or PET/CT imaging, no more than 3 months before study enrollment
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