Lung Cancer Clinical Trial
A Study of the HSP90 Inhibitor, STA-9090 in Subjects With Stage IIIB or IV Non-Small Cell Lung Cancer (NSCLC)
Summary
This is a phase 2 study of the HSP90 inhibitor, STA-9090 (ganetespib) in subjects with stage IIIB or IV non-small cell lung cancer (NSCLC).
Eligibility Criteria
Inclusion Criteria:
Pathologically confirmed diagnosis of Stage IIIB (with pleural effusion) or Stage IV NSCLC with measurable disease by RECIST and evidence of progression
Availability of tissue for analysis
ECOG Performance Status 0 or 1
Adequate organ function as defined in the protocol.
Must be at least 18 years old and able and willing to sign a written informed consent document
Exclusion Criteria:
Poor venous access requiring an indwelling catheter for study drug administration
Women who are pregnant or lactating
Ventricular ejection fraction < or = to 55% at baseline
Any uncontrolled intercurrent illness
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There are 21 Locations for this study
Tucson Arizona, 85724, United States
Hot Springs Arkansas, 71913, United States
Duarte California, 91010, United States
Santa Monica California, 90404, United States
Aurora Colorado, 80045, United States
Atlanta Georgia, 30322, United States
Chicago Illinois, 60612, United States
Chicago Illinois, 60637, United States
Baltimore Maryland, 21231, United States
Boston Massachusetts, 02114, United States
Boston Massachusetts, 02115, United States
Boston Massachusetts, 02215, United States
Las Vegas Nevada, 89135, United States
Hackensack New Jersey, 07601, United States
Chapel Hill North Carolina, 27599, United States
Winston Salem North Carolina, 27103, United States
Portland Oregon, 97239, United States
Hershey Pennsylvania, 17033, United States
Nashville Tennessee, 37212, United States
Dallas Texas, 75390, United States
Seattle Washington, 98104, United States
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