Lung Cancer Clinical Trial

A Study of the HSP90 Inhibitor, STA-9090 in Subjects With Stage IIIB or IV Non-Small Cell Lung Cancer (NSCLC)

Summary

This is a phase 2 study of the HSP90 inhibitor, STA-9090 (ganetespib) in subjects with stage IIIB or IV non-small cell lung cancer (NSCLC).

View Eligibility Criteria

Eligibility Criteria

Inclusion Criteria:

Pathologically confirmed diagnosis of Stage IIIB (with pleural effusion) or Stage IV NSCLC with measurable disease by RECIST and evidence of progression
Availability of tissue for analysis
ECOG Performance Status 0 or 1
Adequate organ function as defined in the protocol.
Must be at least 18 years old and able and willing to sign a written informed consent document

Exclusion Criteria:

Poor venous access requiring an indwelling catheter for study drug administration
Women who are pregnant or lactating
Ventricular ejection fraction < or = to 55% at baseline
Any uncontrolled intercurrent illness

Study is for people with:

Lung Cancer

Phase:

Phase 2

Estimated Enrollment:

113

Study ID:

NCT01031225

Recruitment Status:

Completed

Sponsor:

Synta Pharmaceuticals Corp.

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There are 21 Locations for this study

See Locations Near You

Arizona Cancer Center; University of Arizona
Tucson Arizona, 85724, United States
Genesis Cancer Center
Hot Springs Arkansas, 71913, United States
City of Hope Medical Center
Duarte California, 91010, United States
UCLA Health System
Santa Monica California, 90404, United States
University of Colorado Cancer Center
Aurora Colorado, 80045, United States
Emory University- Winship Cancer Institute
Atlanta Georgia, 30322, United States
Rush University Medical Center
Chicago Illinois, 60612, United States
University of Chicago Medical Center
Chicago Illinois, 60637, United States
Johns Hopkins Sidney Kimmel Comprehensive Cancer Center
Baltimore Maryland, 21231, United States
Massachusetts General Hospital
Boston Massachusetts, 02114, United States
Dana Farber Cancer Institute
Boston Massachusetts, 02115, United States
Beth Israel Deaconess Medical Center
Boston Massachusetts, 02215, United States
Nevada Cancer Institute
Las Vegas Nevada, 89135, United States
Hackensack University Medical Center
Hackensack New Jersey, 07601, United States
University of North Carolina, Lineberger Comprehensive Cancer Center
Chapel Hill North Carolina, 27599, United States
Piedmont Hematology Oncology Associates
Winston Salem North Carolina, 27103, United States
Oregon Health and Science University
Portland Oregon, 97239, United States
Penn State Hershey Cancer Institute
Hershey Pennsylvania, 17033, United States
Vanderbilt-Ingram Cancer Center
Nashville Tennessee, 37212, United States
UT Southwestern Medical Center
Dallas Texas, 75390, United States
Swedish Medical Center
Seattle Washington, 98104, United States

How clear is this clinincal trial information?

Study is for people with:

Lung Cancer

Phase:

Phase 2

Estimated Enrollment:

113

Study ID:

NCT01031225

Recruitment Status:

Completed

Sponsor:


Synta Pharmaceuticals Corp.

How clear is this clinincal trial information?

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