Lung Cancer Clinical Trial

Clinical Trial Finder Lung Cancer Trials

Analysis of Biopsy Specimens to Study Responses to PD-1 or PD-L1 Therapies

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Summary

The purpose of this study is to attempt to obtain an on-treatment biopsy in participants with non-small cell lung cancer who are receiving standard treatment with a drug that targets the PD-1 or PD-L1 protein.

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Eligibility Criteria

Inclusion Criteria:

Pathologically confirmed newly diagnosed or recurrent advanced Non Small Cell Lung Cancer/NSCLC that is PI-L1 high by immunohistochemistry (PD-L1 >/= 50%)
Intended treatment with a PD-(L)1 inhibitor
Age >/= 18 years
Karnofsky Performance Status >/= 70% and medically fit to undergo a biopsy procedure

Exclusion Criteria:

Any medical condition or any sites of disease that would preclude a biopsy
Pregnant or breastfeeding women
Cognitively impairment affecting ability to understand and provide informed consent
Prior PD-(L)1 blockade treatment
Chemotherapy within 6 months prior to enrollment

Study is for people with:

Lung Cancer

Study ID:

NCT03877250

Recruitment Status:

Withdrawn

Sponsor:

Memorial Sloan Kettering Cancer Center

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There are 6 Locations for this study

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Memoral Sloan Kettering Basking Ridge (Consent and Follow up)
Basking Ridge New Jersey, 07920, United States
Memoral Sloan Kettering Monmouth (Consent and Follow up)
Middletown New Jersey, 07748, United States
Memorial Sloan Kettering Bergen (Consent and Follow up)
Montvale New Jersey, 07645, United States
Memorial Sloan Kettering Cancer Center @ Suffolk (Consent Only)
Commack New York, 11725, United States
Memoral Sloan Kettering Westchester (Consent & Follow Up)
Harrison New York, 10604, United States
Memorial Sloan - Kettering Cancer Center (Consent and follow-up)
New York New York, 10021, United States
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How clear is this clinincal trial information?

Study is for people with:

Lung Cancer

Study ID:

NCT03877250

Recruitment Status:

Withdrawn

Sponsor:


Memorial Sloan Kettering Cancer Center

How clear is this clinincal trial information?

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