Lung Cancer Clinical Trial

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AZD6244 Versus Pemetrexed (Alimta®) in Patients With Non-small Cell Lung Cancer, Who Have Failed One or Two Prior Chemotherapy Regimen

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Summary

The purpose of this study is to assess the effect and safety of AZD6244(ARRY-142886)versus pemetrexed in the second or third line treatment of advanced Non-Small Cell Lung Cancer. Following baseline assessments, a minimum of 64 patients in approximately 5-6 centers from the US will be treated with either AZD6244 or pemetrexed. Treatment will be continued for as long as patients receive clinical benefit.

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Eligibility Criteria

Inclusion Criteria:

Diagnosed with non-small cell lung cancer
Previously received one or two chemotherapeutic treatments

Exclusion Criteria:

Previous therapy with MEK inhibitor or pemetrexed
Any recent surgery, unhealed surgical incision or severe condition such as uncontrolled cardiac disease or chronic gastrointestinal diseases

Study is for people with:

Lung Cancer

Phase:

Phase 2

Estimated Enrollment:

88

Study ID:

NCT00372788

Recruitment Status:

Completed

Sponsor:

AstraZeneca

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There is 1 Location for this study

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Research Site
Los Angeles California, , United States
Research Site
Ann Arbor Michigan, , United States
Research Site
New York New York, , United States
Research Site
Nashville Tennessee, , United States
Research Site
Plovdiv , , Bulgaria
Research Site
Sofia , , Bulgaria
Research Site
Varna , , Bulgaria
Research Site
Cluj-Napoca , , Romania

How clear is this clinincal trial information?

Study is for people with:

Lung Cancer

Phase:

Phase 2

Estimated Enrollment:

88

Study ID:

NCT00372788

Recruitment Status:

Completed

Sponsor:


AstraZeneca

How clear is this clinincal trial information?

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