Lung Cancer Clinical Trial
Blood Samples From Patients With Non-Small Cell Lung Cancer and From Healthy Volunteers
Summary
RATIONALE: Studying samples of blood from patients with cancer in the laboratory may help doctors learn more about changes that occur in DNA and identify biomarkers related to cancer.
PURPOSE: This research study is looking at blood samples from patients with non-small cell lung cancer and from healthy volunteers.
Full Description
OBJECTIVES:
Measure plasma cathepsin D levels in patients with non-small cell lung cancer and in healthy volunteers using mass spectometry.
Measure fatty acid synthase levels in these patients and healthy volunteers using mass spectometry.
OUTLINE: Blood samples are collected from patients and healthy volunteers to measure the levels of cathepsin D and fatty acid synthase by proteomic profiling and mass spectrometry.
Eligibility Criteria
Inclusion Criteria:
Non-Small Cell Lung Cancer Patients
Documented diagnosis of non-small cell lung cancer, any stage and any time point in the course of treatment (i.e., at diagnosis, during any treatment, and during post treatment surveillance)
Measurable disease by CT scan within the past 4 weeks
Healthy volunteer
Non-smoking, defined as < 5 packs/year history of smoking and cessation of smoking ≥ 6 months ago OR a never smoker
Not regularly exposed (i.e., daily) to second-hand smoke
Exclusion Criteria:
Severe underlying lung disease (i.e., chronic obstructive pulmonary disease with FEV_1 < 1.0 L, pulmonary fibrosis, bronchiectasis, cystic fibrosis, etc.) as determined by enrolling researcher.
Written consent must be given for both subjects and controls.
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There is 1 Location for this study
Minneapolis Minnesota, 55455, United States
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