Lung Cancer Clinical Trial

DNA Repair and Genetic Susceptibility to Lung Cancer

Summary

The purpose of this study is to help us better understand the cellular changes that may lead to the development of lung cancer. We want to compare people with a second primary lung cancer with those who have only a first primary lung cancer. We hope to use the information obtained in this study as the basis for future studies and will not regard the results from this study as final.

We will analyze your blood cells and DNA to measure the changes in several genes that we believe may be involved in lung cancer. We also want to evaluate the capacity for your DNA to repair itself.

View Eligibility Criteria

Eligibility Criteria

Inclusion Criteria:

Cases will be eligible for inclusion if:
They have been diagnosed with a second primary lung cancer, and
They speak English or a language for which we have a translated consent form, and
They understand and agree to sign informed consent, and
They agree to give us a blood sample, and
They agree to give us a tissue sample when part of normal clinical procedures, and
They agree to complete the study questionnaires, and
They agree to have their pathology information reviewed. This could include biopsy specimens.

Controls will be eligible for inclusion if

They have been diagnosed with a first primary lung cancer, and
They speak English or a language for which we have a translated consent form, and
They understand and agree to sign informed consent, and
They agree to give us a blood sample, and
They agree to give us a tissue sample when part of normal clinical procedures, and
They agree to complete the study questionnaires,
They agree to have their pathology information reviewed. This will could include biopsy specimens.

Exclusion Criteria:

Subjects who do not meet the inclusion criteria as either cases or controls will not be eligible for this study.
Control subjects who have a history of another cancer, other than nonmelanoma skin cancer or a first primary lung cancer, will not be eligible for this study.
Control subjects who otherwise meet the eligibility requirements above but who have had chemotherapy and/or are currently being treated with chemotherapy will be excluded from the functional assay, but not from the genotyping.

Study is for people with:

Lung Cancer

Estimated Enrollment:

218

Study ID:

NCT00611598

Recruitment Status:

Active, not recruiting

Sponsor:

Memorial Sloan Kettering Cancer Center

Check Your Eligibility

Let’s see if you might be eligible for this study.

What is your age and gender ?

Submit

There is 1 Location for this study

See Locations Near You

Memorial Sloan Kettering Cancer Center
New York New York, 10065, United States

How clear is this clinincal trial information?

Study is for people with:

Lung Cancer

Estimated Enrollment:

218

Study ID:

NCT00611598

Recruitment Status:

Active, not recruiting

Sponsor:


Memorial Sloan Kettering Cancer Center

How clear is this clinincal trial information?

×

Introducing, the Journey Bar

Use this bar to access information about the steps in your cancer journey.